Results 171 to 180 of about 2,103,567 (340)

Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi, Caroline Gochanour, Seung Ho Choi, Hyunkeun Cho, Chelsea Caspell‐Garcia, Christopher Coffey, Michael Brumm, David‐Erick Lafontant, Yuge Xiao, Thomas Tropea, John Seibyl, Caroline Tanner, Charles S. Venuto, Karl Kieburtz, Lana M. Chahine, Kathleen L. Poston, Andrew Siderowf, Kenneth Marek, Tanya Simuni, The Parkinson's Progression Markers Initiative   +19 more
wiley   +1 more source

Topology optimization of supporting structure for seismic response reduction of an arch

, 2016
Yuji Miyazu, Makoto Ohsaki, Seita Tsuda
openalex   +2 more sources

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source

The impact analysis of energy industry structure optimization on urban low-carbon transition. [PDF]

Carbon Balance Manag
Fan Q, Wu X.
europepmc   +1 more source

In search of an ideal template for therapeutic genome editing: A review of current developments for structure optimization. [PDF]

Front Genome Ed, 2023
Shakirova A, Karpov T, Komarova Y, Lepik K.   +3 more
europepmc   +1 more source

Topology Optimization of Thin-Walled Structures Under Static/Crash Loading Case in the Hybrid Cellular Automaton Framework

, 2017
Duo Zeng, Fabian Duddeck
openalex   +2 more sources

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source

Structure optimization design for supporting ring of casing head hanger in extra deep oil wells. [PDF]

Sci Rep
Feng S, Zou G, Liu W, Wei J, Liu F, Zhang Y, Guo C.   +6 more
europepmc   +1 more source

Structure Optimization of a Fe-Mn-Pd Alloy by Equal-Channel Angular Pressing for Biomedical Use. [PDF]

Materials (Basel), 2022
Rybalchenko O, Anisimova N, Martynenko N, Rybalchenko G, Kiselevskiy M, Tabachkova N, Shchetinin I, Raab A, Dobatkin S.   +8 more
europepmc   +1 more source

A Study on the Architectural Design of Immersion-Basin Parking Structures and Optimized Operational Systems for EV Fire Suppression

Younsang Hwang
openalex   +1 more source