Results 121 to 130 of about 23,285,507 (332)
Experimental study of pressure distributions due to the breaking wave impacts [PDF]
, 2012 Kisacik, Dogan +2 more
core +2 more sources
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Identifying Problematic Soils Using Compressibility and Suction Characteristics
BuildingsThe major problematic soils in semi-arid regions include expansive soils and collapsible soils. These two types of soils cause problems and are hazardous for buildings when moisture is introduced following a dry or semi-dry season. In order to assess the
Muawia Dafalla, Ahmed M. Al-Mahbashi
doaj +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Reliability of demolition by controlled implosions [PDF]
Constructii: Journal of Civil Engineering Research, 2014 The achievement of demolition works on structures, by authorized personnel, using explosives, implies a combination of risks that exist on any construction site with the specific risks of work with explosives. These specific risks are generated mainly by
Adrian SIMION, Claudiu-Sorin DRAGOMIR
doaj
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Structural Harm, Structural Injustice, Structural Repair
Abstract In Chapter 1, ‘Structural Harm, Structural Injustice, Structural Repair’, Jonathan Wolff explores the nature of structural injustice and how it tends to come into being. For Wolff, structural harm is not an injustice but rather a mere unfortunate outcome of structural processes.
openaire +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source