Results 111 to 120 of about 1,643,762 (318)
Higher Dimensional Transition Systems
We introduce the notion of higher dimensional transition systems as a model of concurrency providing an elementary, set-theoretic formalisation of the idea of higher dimensional transition.
Cattani, G.L. +3 more
core
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Visually Embodying Well-Typedness of Algebraic Data Structures through Maramafication
This paper presents a maramafication of an essential part of FPLs: the construction of well-typed algebraic data structures based on type definitions with at most one type parameter.
Sub Intelligent Systems +3 more
core
Discrete exterior geometry approach to structure-preserving discretization of distributed-parameter port-Hamiltonian systems [PDF]
This paper addresses the issue of structure-preserving discretization of open distributed-parameter systems with Hamiltonian dynamics. Employing the formalism of discrete exterior calculus, we introduce a simplicial Dirac structure as a discrete analogue
Seslija, Marko, +11 more
core +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Absorbing Sets in Coalitional Systems [PDF]
The purpose of this paper is twofold: First, to present an approach and a solution for analyzing the stability of coalition structures: We define a coalitional system (a set and a binary relation on that set) that explains the transitions between ...
Olaizola Ortega, María Norma +2 more
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Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Statistical energy analysis of engineering structures
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.This thesis examines the fundamental equations of the branch of linear oscillatory dynamics known as Statistical Energy Analysis (SEA).
Keane, A.J, Keane, Andrew John
core
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source

