Results 191 to 200 of about 1,274,598 (268)

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

FEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde, Unai Alduntzin, Gorka Prieto, Ugo Mayor   +3 more
wiley   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Open Molecular Crystals 2025 (OMC25) dataset and models. [PDF]

Sci Data
Gharakhanyan V, Barroso-Luque L, Yang Y, Shuaibi M, Michel K, Levine DS, Dzamba M, Fu X, Gao M, Liu X, Ni H, Noori K, Wood BM, Uyttendaele M, Boromand A, Zitnick CL, Marom N, Ulissi ZW, Sriram A.   +18 more
europepmc   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Composition and Structural Design of Magnetic Alloy/Composites for High-Performance Microwave Absorption: A Review. [PDF]

Nanomaterials (Basel)
Zhou M, Zhou Z, Cheng H.
europepmc   +1 more source

Photodissociation and Infrared Spectroscopy of U⁺(CO₂)_<i>n</i>, UO⁺(CO₂)_<i>n</i>, and UO²⁺(CO₂)_<i>n</i> Cation-Molecular Complexes. [PDF]

J Phys Chem A
Marks JH, Odonkor RB, Dynak NJ, Duncan MA.   +3 more
europepmc   +1 more source

Improving Protein Structure Determination by Integrating Ensemble-Driven Molecular Dynamics with Chemical Shift-Based Restraints. [PDF]

J Chem Inf Model
Gadanecz M, Fazekas Z, Menyhárd DK, Perczel A.   +3 more
europepmc   +1 more source

Complexities in Hoffa Fracture Management: A Case Report on Diagnosis and Fixation Technique. [PDF]

Case Rep Orthop
Ratra R, Goyal AK.
europepmc   +1 more source

Analytical wave families and stability dynamics in a modified complex Ginzburg-Landau model via the modified extended direct algebraic method. [PDF]

Sci Rep
Rateb AE, Ahmed HM, Darwish A, Ammar M, Rabie WB.   +4 more
europepmc   +1 more source