Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng +2 more
wiley +1 more source
Morphological changes in smectic liquid crystal microstructures.
Sato D +4 more
europepmc +1 more source
Microhydration Effects on Hemibonds in [H<sub>2</sub>O-X]<sup>+</sup>-(H<sub>2</sub>O)<sub><i>n</i></sub> (X = O<sub>2</sub> and CS<sub>2</sub>; <i>n</i> = 0-2): Infrared Spectroscopic Characterization toward Understanding Charge-Resonance Interactions in Aqueous Environments. [PDF]
Hosoda T, Fujii A.
europepmc +1 more source
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti +3 more
wiley +1 more source
Safe Sport in Mediterranean Contexts: Cultural Logics of Harm, Silence, and Authority. [PDF]
Chroni SA +15 more
europepmc +1 more source
Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi +7 more
wiley +1 more source
Cross-national variations and demographic disparities in health surveillance system performance: a comparative analysis of OECD member countries. [PDF]
Çelik AA, Balcioğlu YS, Altindağ E.
europepmc +1 more source
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
DFTB Parametrization at the Example of Platinum-Implementation, Validation and Practical Considerations. [PDF]
Purtscher FRS +4 more
europepmc +1 more source

