Results 111 to 120 of about 441,298 (300)

The Career of Vernon Briggs, Jr.: A Liberal Economist’s Struggle to Reduce Immigration [PDF]

open access: yes, 2012
[Excerpt] At the conclusion of Cornell’s spring semester in 2007, Briggs ended his 47 years of college teaching. As he retired, Cornell honored him with emeritus status.
Kammer, Jerry
core   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

open access: yesMolecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Resistance on the battlefield: the lives of the marginalized in Capão Pecado

open access: yesTravessias, 2020
This article proposes a reflection on the life and cultural representation of the marginalized in the work Capão Pecado de Ferréz, as well as the cultural relations that constitute conflicting dialogues.
Francinaldo Pereira da Silva   +1 more
doaj  

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

The (Possible) Function of the Beatitude of the Poor in the Context of the Struggle against Poverty

open access: yesActa Theologica, 2013
The article focuses on the beatitude of the poor in the social and religious context of historical Jesus. The original version of this makarism has to be seen as a religious statement which is not meant as a program of social reform. Yet it has political and socio-ethical implications as it connects the poor with God and his kingdom.
openaire   +5 more sources

Naming the problem [PDF]

open access: yes, 2005
Everyone, even the most die-hard defender of the established order recognizes that we face serious social and environmental problems. The news media regularly circulate the latest figures on the latest social problems.
Hubbard, G., Miller, David
core  

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

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