Results 111 to 120 of about 443,266 (330)
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Are the media globalizing political discourse? The war on terrorism case study [PDF]
, 2004 The paper challenges the claim that an increasingly global media is creating a homogenisation of political discourses at the international level. In particular, it explores the extent to which the U.S. government managed to affect global perceptions of
Archetti, C
core +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
HUMAN TRAFFICKING – SLAVERY OF THE 21st CENTURY [PDF]
Hum, 2017 This paper deals with human trafficking which is a complex social phenomenon whose dynamics, mobility and organization in national and international dimensions represents a complex and serious problem of contemporary society.
Irena Musa
doaj
The Career of Vernon Briggs, Jr.: A Liberal Economist’s Struggle to Reduce Immigration [PDF]
, 2012 [Excerpt] At the conclusion of Cornell’s spring semester in 2007, Briggs ended his 47 years of college teaching. As he retired, Cornell honored him with emeritus status.
Kammer, Jerry
core +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Resistance on the battlefield: the lives of the marginalized in Capão Pecado
Travessias, 2020 This article proposes a reflection on the life and cultural representation of the marginalized in the work Capão Pecado de Ferréz, as well as the cultural relations that constitute conflicting dialogues.
Francinaldo Pereira da Silva +1 more
doaj
Relational Work in the Struggle Against Poverty: Balancing Scholarly Critiques and Emancipatory Practices in the Nonprofit Sector [PDF]
, 2019 Michael Jindra +2 more
openalex +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source