Results 51 to 60 of about 12,309 (251)
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
A épica da pobreza: mulheres imigrantes
Storia delle Donne, 2018 Between the nineteenth and the twentieth centuries the Italian emigration to the Brazilian state of Rio Grande do Sul was predominantly familiar and included in the system of small peasant properties planned by the local government.
Loraine Slomp Giron
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Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Ecology versus poverty: The loser is …
Verbum et EcclesiaIn the battle between ecology and poverty, ecology will always be the loser. This statement is proved in this article by using the Kruger National Park in South Africa as an example. In recent times, poaching of rhinos, snaring of other wildlife, and the
Johan M. van der Merwe
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Does Black theology have a role to play in the democratic South Africa?
Acta Theologica, 2016 Black theology was conceived in South Africa in the mid-1960s and flourished from the 1970s, when White supremacy perpetuated by the apartheid state was at its zenith.
R. T. H. Dolamo
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Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
Breaking the Cycle of Poverty for Developing a New Africa
African Theological Journal for Church and Society, 2023 The focus of the United Nations’ Sustainable Development Goals (SDGs) initiative since 2015 has been “Eradicating extreme poverty for all people everywhere by 2030,” if not wholly, then at least reduce it to an ambitious 3% of the world’s population ...
Okechukwu Nzenwa Okorie, Victor Umaru
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