Results 151 to 160 of about 661,328 (352)

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

Efficacy of Intermittent Theta‐Burst Stimulation for Prolonged Disorders of Consciousness: A Prospective, Randomized, Controlled Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Emerging evidence suggests that low‐frequency neural oscillations are dynamically regulated by consciousness levels, with the recovery of low cortical activity potentially serving as a neurophysiological substrate for conscious emergence. Targeted enhancement of these low‐frequency rhythms in patients with disorders of consciousness
Chuan Xu, Jun Hu, Qianqian Wu, Min Wu, Yamei Yu, Hangcheng Li, Jian Gao, Jingqi Li, Nai Ding, Jie Yu, Benyan Luo   +10 more
wiley   +1 more source

A Design Case of Scaffolding Hybrid/Online Student-Centered Learning with Multimedia

Journal of Educators Online, 2017
Implementing student-centered learning in hybrid/online settings is very challenging due to the physical separation of instructor and students. This article discusses the need for instructors to provide scaffolds and multimedia modules to facilitate ...
E-Ling Hsiao, Peter Mikolaj, Ya-Ting Shih   +2 more
doaj  

PENERAPAN ASESMEN REPRESENTASI MELALUI PENDEKATAN STUDENT CENTERED LEARNING (SCL) UNTUK MENINGKATKAN PENGUASAAN KONSEP DAN KEMAMPUAN PSIKOMOTOR

Jurnal Kumparan Fisika, 2020
Abstrak   Penelitian ini adalah penelitian tindakan kelas (PTK). Penelitian ini bertujuan untuk mendeskripsikan penguasaan konsep dan kemampuan psikomotor mahasiswa menerapkan asesmen representasi melalui pendekatan Student Centered Learning pada ...
Rosane Medriati, Eko Risdianto
doaj  

Incorporating effective teaching pedagogies to improve learning and teaching approaches globally [PDF]

, 2019
CONTEXT From secondary to tertiary level, educational development relies comprehensively on teaching elements and strategies, it is about learning to think and act in ways that will apply safety measures to the future wellbeing of our students. Learner
AL-Rawi, Mohammad, Khanna, Jai, Kumari, Sarla, Moridnejad, Maryam   +3 more
core  

Paramagnetic Rim Lesions Are Associated With Trans‐Synaptic Degeneration of the Visual Pathway in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Retrograde trans‐synaptic degeneration (rTSD) from posterior visual pathway lesions in multiple sclerosis (MS) is characterized by hemi‐macular ganglion cell‐inner plexiform layer (GCIPL) thinning and contralateral visual field loss.
Abdul Jaber Tayem, Angel Liu, Sargis Manukyan, Mustafa Subhi, Elaina Luskin, Bryan Quah, Sreekanth Madhusoodhanan Nair, Arzu C. Has Silemek, Gabriela Zabala, Yujie Cui, Laura Locke, Paula Barreras, Marwa Kaisey, Vinicius Calsavara, Daniel S. Reich, Nancy L. Sicotte, Pascal Sati, Omar Al‐Louzi   +17 more
wiley   +1 more source

Pengembangan Kerangka Kerja TPACK Pada Materi Koloid Untuk Meningkatkan Aktivitas Pembelajaran Dalam Mencapai HOTS Siswa [PDF]

, 2014
Chemistry learning particularly colloid material has a scientific topic that measuring up to abstract and emphasizes the mastery of concepts until the microscopic level (molecular) symbolic. Thus, the implementation of learning need to be completed.
Hayati, D. K. (Dwi), Lukman, A. (Aprizal), Sutrisno, S. (Sutrisno)   +2 more
core  

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang, Huiying Wang, Zhizheng Zhuo, Ai Guo, Ke Lv, Decai Tian, Chao Chai, Yunyun Duan, Shuang Xia   +8 more
wiley   +1 more source

Stan wdrożenia modelu nauczania skoncentrowanego na studentach i studentkach na polskich uczelniach wyższych [PDF]

, 2013
Student-Centered Learning, i.e. education concentrated on students, is one of the basic ideas influencing the evaluation of higher education in Europe within the program of the Bolognese Process, and on the local level - of works on the Domestic ...
Barzykowski, Krystian, Grzymała-Moszczyńska, Joanna, Kwiecień, Katarzyna, Rataj, Aleksandra   +3 more
core   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source