Results 61 to 70 of about 8,115,676 (242)

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Evaluation of a student-run smoking cessation clinic for a medically underserved population

BMC Research Notes, 2011
Background Smoking is common among medically underserved populations. Accessible resources to encourage and support smoking cessation among these patients are limited.
Ebbert Jon O, Lough Lindsay E, McLeod Thomas G   +2 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

ISE Annual Student Recruitment Survey 2018 [PDF]

, 2018
This paper sets out the findings of the Institute of Student Employers 2018 recruitment ...
Institute of Student Employers
core  

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Assessing Medical Student Attitudes Toward Intimate Partner Violence and Sexual Assault Following Protocol Training in a Student-Run Clinic Network

Background: Intimate Partner Violence (IPV) and Sexual Assault (SA) represent critical challenges in clinical settings, impacting patient safety and well-being.
Rajvi Kumar, Mahant Malempati
core   +1 more source

Associated SDOH needs of patients without health insurance and experiencing food insecurity

Discover Social Science and Health
Although patients experiencing food insecurity commonly screen positive for a myriad of social determinants of health (SDOH) needs and chronic medical conditions influenced by diet, few studies have investigated associations within both uninsured and ...
Suma K. Thareja, Spenser Marting, William Davies, Santhosi Samudrala, Ramsey Rayes, Marie Balfour, Ana Mia Corujo-Ramirez, Frances Carter, Benjamin Liu, Dylan Trinh, Thomas Ritter, Jessica Miller, Coleman Fine, Rebecca Lundh, Staci A. Young   +14 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

One Health clinic challenges and evolution: increasing access to care for people and pets in a rural community in Northern California

Frontiers in Veterinary Science
A student-run, free One Health clinic (OHC) improves access to care for people and pets while providing increased training opportunities for interprofessional students in the areas of spectrum of care, contextualized care, cultural humility, ethical ...
Kristin Jankowski, Kimberly Aguirre Siliezar, Jeannie A. Knuchell, Adrian Duenas-Ramirez, Jennifer J. Edwards, Jonathan D. Dear   +5 more
doaj   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source