Results 111 to 120 of about 1,465,873 (311)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Social movements and student movement

open access: yes, 2012
This paper discusses how and to what extent the group of student representative entities can be considered a social movement. To this end, we analyze some of the definitions of these social movements attempting to comprehend from its meanings the character of student mobilization and the reason why it can be considered a social movement in only given ...
openaire   +1 more source

Design and semantics of form and movement (DeSForM 2006) [PDF]

open access: yes, 2006
Design and Semantics of Form and Movement (DeSForM) grew from applied research exploring emerging design methods and practices to support new generation product and interface design.
Feijs, Loe   +2 more
core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Student activism and the 13th Malaysian General Election: the second civil society wave after 1969 [PDF]

open access: yes, 2015
The 13th Malaysian General Election held on 5 May, 2013 witnessed the revival of the student movement in Malaysia. Civil society activism had been on the wane for more than 40 years as the student movement had been shackled by the Universities and ...
Fadzil, Mohd Fauzi, Ku Samsu, Ku Hasnita
core  

The 1968 Movement in Mexico ‎- A Documentary Study-‎

open access: yesمجلة جامعة الأنبار للعلوم الإنسانية
Aims: This study aims to investigate the historical importance of the 1968 ‎movement in Mexico, which represented a pivotal turning point in the ‎country's political and social history.
Saba Rabeea Ahmed
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Impact of Incorporating Movement and Hands-On Experiences on Student Learning [PDF]

open access: yes, 2011
This inquiry took place during my student teaching experience. While student teaching, I explored the use of movement and hands-on experiences throughout the curriculum as a way to effectively engage second graders in learning.
Deverman, Cara   +1 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Using digital storytelling as a methodology for the introduction of socially responsible graphic design in a University Bachelor of Computer Graphic Design Programme [PDF]

open access: yes, 2009
This paper case studies the pedagogical methodology for a digital storytelling project involving final semester Bachelor of Computer Graphic Design students and students from a community based charitable arts trust. A young artist is paired with a senior
Vanderschantz, Nicholas
core   +1 more source

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