Results 51 to 60 of about 143,675 (273)
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Social degradation : a study of the handicap of poverty /
, 1912 Intended for use as a text in study circles of the Student Christian Movement. Cf.
Student Christian Movement of Great Britain and Ireland. +1 more
core
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
The man in the revolution: Kazan guberniya. 1905–1907. The excursion via a new book
Историческая этнология, 2016 This article provides a brief overview the monograph The Man in the Revolution: Kazan Guberniya. 1905–1907 (see: Chelovek v revolyutsii: Kazanskaya guberniya: v 2- kh tomakh. T.1. 1905–1907 gg. / pod red. L.R. Gabdrafikovoy.
Liliya R. Gabdrafikova
doaj
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Rethinking the Rat Trilogy: Detachment, Commitment and Haruki Murakami’s Politics of Subjectivity
New Voices in Japanese Studies, 2017 The career of novelist Haruki Murakami has conventionally been divided into two periods: detachment and commitment. Murakami’s transition to commitment, in the sense of a social engagement with a defined political sensibility, is generally seen to begin ...
A. K. Byron
doaj +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Lateral, 2013 Images from an art exhibition inspired by the 2010–2011 University of Puerto Rico student Movement.
Isamar Abreu +11 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source