Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Accelerating writing engagement: a design framework for operationalizing student engagement in writing instruction. [PDF]
Marine J +3 more
europepmc +1 more source
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Socio-emotional readiness and classroom ecology in 5th-grade EFL classrooms: a responsive evaluation of the English curriculum in Türkiye. [PDF]
Kuzu HA, Egmır E.
europepmc +1 more source
Pastoral Care Provision for Medical Students: What Is the Role of the Clinical Teaching Fellow? [PDF]
McSwiney NT, Taylor N, Jennings S.
europepmc +1 more source
Exploring the Barriers Faced by Medical Students and the Impact of Their Involvement in a Widening Participation Charity. [PDF]
James E, Haque E.
europepmc +1 more source
An Analysis of the Career Pathway of Clinical Laboratory Scientists: Identifying Access Barriers and Best Practice to Increase Diversity in the Workforce. [PDF]
O'Connor JA.
europepmc +1 more source
Ana-Art Rangoli as an Active Learning Strategy in Undergraduate Anatomy Education: An Innovative Educational Approach. [PDF]
Bokan RR +6 more
europepmc +1 more source

