Results 251 to 260 of about 5,548,448 (344)

Nature‐Inspired Nanostructures from Multiple‐Species Biomembranes: Rational Engineering and Therapeutic Applications in Tumor‐Targeted Nanomedicine

open access: yesAdvanced Science, EarlyView.
Naturally derived biomembrane nanostructures by mimicking evolutionarily optimized biological architectures could effectively suppress tumor growth and have emerged as a compelling strategy in translational biomedicine. This review provides a systematic overview of rational design and underlying antitumor therapeutic mechanisms of mammalian cells ...
Xiaodan Wei   +10 more
wiley   +1 more source

FOXM1 Protects Against Myocardial Ischemia‐Reperfusion Injury in Rodent and Porcine Models by Suppressing MKRN1‐Dependent LKB1 Ubiquitination

open access: yesAdvanced Science, EarlyView.
FOXM1 maintains mitochondrial bioenergetic function by inhibiting MKRN1‐mediated ubiquitination of LKB1 in cardiomyocytes. Loss of FOXM1 in cardiomyocytes results in upregulation of MKRN1, which enhances LKB1 ubiquitination and disrupts AMPK signaling and energy metabolism pathways. Conversely, FOXM1 overexpression preserves mitochondrial bioenergetics
Shuai Song   +17 more
wiley   +1 more source

Behavioral determinants of dental and facial esthetic self-perception among an academic population: a cross-sectional study. [PDF]

open access: yesBMC Psychol
Mafla AC   +6 more
europepmc   +1 more source

High‐Density Flexible Neural Implants with Submicron Feedline Resolution

open access: yesAdvanced Electronic Materials, EarlyView.
Optimization of microfabrication methods using optical contact lithography (OCL) and electron beam lithography (EBL) enables the fabrication of 64‐channel, high‐density, parylene‐C‐based intracortical implants with submicron feedlines as narrow as 400 and 50 nm, respectively.
Lina Koschinski   +10 more
wiley   +1 more source

Enhanced and Durable Light‐Driven Hydrogen Evolution by Cobalt‐Based Prussian Blue Analogs in Phospholipid Bilayers

open access: yesAdvanced Energy and Sustainability Research, EarlyView.
Light‐driven H2 evolution catalysis is reported for oleylamine‐capped MCo Prussian blue analogs (PBAs, M = Ni, Co, Zn, Cu) within phospholipid bilayers and using a ruthenium‐based amphiphilic photosensitizer. The hydrophobic interactions between the active units bring them in close proximity facilitating catalysis.
Subrata Mandal   +5 more
wiley   +1 more source

Does surgical intervention contribute to survival for patients with para‐aortic lymph node metastasis from colorectal cancer?

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
Overall survival of patients who underwent surgical resection was significantly better compared to that of patients who underwent chemotherapy without surgical resection. These results highlight the benefit of surgical intervention to survival for patients with isolated para‐aortic lymph node metastasis or with resectable liver metastasis.
Akira Ouchi   +39 more
wiley   +1 more source

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