Results 31 to 40 of about 59,701 (244)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Comparative color stability assessment of orthodontic clear aligners: an in vitro study

open access: yesScientific Reports
Objective To evaluate the stain resistance and color stability of four Clear aligners (CA) brands against various beverages at different intervals, along with assessing the elaboration of cleaning agents. Methods In a strictly controlled lab environment,
Nancy Ajwa   +3 more
doaj   +1 more source

Career aspirations of dental students: insights from a multinational study using social cognitive career theory (SCCT)

open access: yesFrontiers in Oral Health
BackgroundDental students' career choices are shaped by many factors, including their personal abilities and goals, environmental factors and the resources available to them.
Abanoub Riad   +37 more
doaj   +1 more source

Validez de constructo y consistencia interna de tres estructuras factoriales y dos sistemas de puntuación del cuestionario de salud general de 12 ítems

open access: yesBiomédica: revista del Instituto Nacional de Salud, 2017
Introducción. El análisis de las propiedades psicométricas de un instrumento reviste importancia para el control de sesgos en la medición. Objetivo.
Miguel Simancas-Pallares   +2 more
doaj   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

A Comparison of Lower Dental Arch Changes Using Two Types of Space Regainers: A Removable Appliance with a Distalizing Screw and a Fixed Double-Banded Appliance

open access: yesInternational Journal of Dentistry, 2022
Aim. The aim of this study was to compare lower dental arch changes using two types of space regainers, including a removable appliance with a distalizing screw and a fixed double-banded appliance. Methods and Materials.
Shabnam Enteghad   +3 more
doaj   +1 more source

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

open access: yesFEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima   +4 more
wiley   +1 more source

CLASSIFICATION OF CHIEF-COMPLAINTS FOR PATIENTS REPORTING AT EMERGENCY DEPARTMENTS

open access: yesJournal of University Medical & Dental College, 2015
: Timely disease detection in case of Infectious Diseases (IDs) can provide sufficient time for disease control activities that might help in controlling the spread of disease to a great extent. Generally, medical diagnostic procedures are time consuming
Muhammad Asif Ali   +2 more
doaj   +2 more sources

Self-Perceived Dentists’ Knowledge of Temporomandibular Disorders in Krakow: A Pilot Study

open access: yesPain Research and Management, 2020
Introduction. The most common nondental orofacial pain conditions are temporomandibular disorders (TMDs). TMD basic examination and clinical management are included in a curriculum of each dentistry programme taught in Poland, but it is not clear how the
Magdalena Osiewicz   +4 more
doaj   +1 more source

Agreement of in vitro orthodontic measurements on dental plaster casts and digital models using Maestro 3D ortho studio software

open access: yesClinical and Experimental Dental Research, 2022
Objective Diagnostic casts are one of the standard components of orthodontic records. But they have several drawbacks such as the need for physical space for storage and the risk of breaking due to their brittle composition.
Elaheh Rafiei   +3 more
doaj   +1 more source

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