Results 31 to 40 of about 370,160 (310)

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Comparative Evaluation of the Effect of Core Type and Antirotational Post on Stress Distribution in an Endodontically Treated Maxillary First Molar: FEA

International Journal of Dentistry, 2022
Background. This study aims to analyze and compare the stress distribution in an endodontically treated maxillary first molar restored with various post and core systems and assess the benefit of the presence of an antirotational post and the effect of ...
Ramin Mosharraf, Amirhossein Fathi, Seyedeh Shiva Botshekan   +2 more
doaj   +1 more source

Student Partnership in E-learning: the Development of Online Resources for Students by Students in Dentistry [PDF]

, 2016
Dentistry is a dynamic and ever changing specialty that has been strongly influenced by developments in technology and therefore our teaching strategies must evolve to keep pace with these changes.
Al-Ani, Ziad, Bragg, Jeremy, Hudda, Shabana, McAllan, Wendy, McKerlie, Robert, Rennie, Evelyn, Ritchie, Martyn, Taha, Amr, Wasige, Claudia   +8 more
core  

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

DENTAL ANXIETY AMONG DENTAL STUDENTS [PDF]

Journal of IMAB - Annual Proceeding (Scientific Papers), 2011
Dental anxiety and dental fear are major factors causing much troubles for the people attending to their own personal health. Statistics show that the 25-26-year-olds experience higher dental anxiety than others. This can be accounted for by the diverse, intense effects of a number of psychological factors in this age range that can cause dental fear ...
openaire   +2 more sources

Dental students' knowledge and perception of elderly in relation to geriatric dentistry training [PDF]

, 2009
Dental students need to be equipped with skills, knowledge and positive attitudes while providing dental care to the elderly. Reports from Ministry of Health Malaysia indicated that the prevalence of dental caries and periodontal disease was high among ...
Husna AA,, Robaiyah K,, Tanti IR,
core  

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Training Dental Students in Dental Amalgam Condensation

The Journal of Nihon University School of Dentistry, 1977
In studying the characteristics of dental amalgam condensation by 36 dental students, it is concluded that : (1) A minimum force of 800 1 b/inch2 is required per condensation stroke in order for the condensation stroke to have any effect on the slow compressive strength test values as a predictor of marginal fracture.(2) A 30, 000 1 b/inch2 slow ...
G, Salvendy, L, Boydstun, G W, Ferguson, S, Birch, P R, Cunningham   +4 more
openaire   +3 more sources

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Assessment of the Periodontal Status among Kota Stone Workers in Jhalawar, India [PDF]

Journal of Clinical and Diagnostic Research, 2013
Context: Periodontal disease is one of the most prevalent dental diseases which affects the adult population of the world, varying only in degree from mild to severe.
Ramesh Nagarajappa, Sudhanshu Sanadhya, Archana J. Sharda, Kailash Asawa, Mridula Tak, Mehak Batra, Hemasha Daryani, Gayathri Ramesh   +7 more
doaj   +1 more source