Results 91 to 100 of about 753,988 (352)
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
The U.S. Science and Technology Workforce [PDF]
[Excerpt] In the 21st century, global competition and rapid advances in science and technology will challenge the scientific and technical proficiency of the U.S. workforce.
Matthews, Christine M, Stine, Deborah D
core +6 more sources
Why are male students less likely to opt for social science courses? : a theory-driven analysis [PDF]
Copyright © 2020 SageIn this article, we discuss the question of why only a few men decide to study social science courses such as social work. While the conceptual base of our analysis includes the theory of planned behaviour and theories centring on ...
Hadjar, Andreas, Haunberger, Sigrid
core +1 more source
Purpose : to prove, develop and check the model of values’ formation of a healthy lifestyle of students in the course of physical training. Material : students participated in an experiment (males - n=108; females - n=120; 18-20 years old).
Imas Y.V.ABCE +5 more
semanticscholar +1 more source
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
The "health education" course is an important part of the baccalaureate curriculum in nursing. It is essential to teach students effective health education in a client oriented way. In order to improve the quality and content of this course, we extracted students descriptions from records of 44 students who had carried out group health education during
Junko, Horikawa +2 more
openaire +3 more sources
On the Sorting of Physicians across Medical Occupations [PDF]
We model the sorting of medical students across medical occupations and identify a mechanism that explains the possibility of differential productivity across occupations.
Courty, Pascal, Marschke, Gerald
core
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
Is More Better? The Impact of Postsecondary Education on the Economic and Social Well-Being of American Society [PDF]
Provides a review of research literature that examines the impact of higher education on individuals and society. Looks at economic and non-economic benefits and costs associated with an increase in public investment in postsecondary ...
Adriane Williams, Watson Scott Swail
core

