Results 111 to 120 of about 904,645 (289)

ETV1 Drives CD4+ T Cell‐Mediated Intestinal Inflammation in Inflammatory Bowel Disease Through Amino Acid Transporter Slc7a5

open access: yesAdvanced Science, EarlyView.
This study identifies the transcription factor ETV1 as a key driver of CD4⁺ T cell‐mediated intestinal inflammation in inflammatory bowel disease (IBD). ETV1 promotes CD4⁺ T cell activation, proliferation, and Th17 differentiation by activating the amino acid transporter SLC7A5, fueling metabolic reprogramming.
Yan Shi   +8 more
wiley   +1 more source

Nursing Students Behind Bars [PDF]

open access: yes, 2019
Virginia Commonwealth University (VCU) School of Nursing and Virginia Commonwealth University Health System (VCUHS) have created a unique partnership in which brand new undergraduate baccalaureate nursing students are completing their first clinical ...
Falk, Mary L.
core   +1 more source

Assessing self-perceptions related to safe medication management among nursing students: an analytical cross-sectional study in Iran

open access: yesBMC Nursing
Background Ensuring patient safety is critical, with safe medication management being a key aspect. However, nursing students often lack the necessary skills for effective medication management.
Reza Nemati-Vakilabad   +3 more
doaj   +1 more source

Targeting Endothelial KDM5A to Attenuate Aging and Ameliorate Age‐Associated Metabolic Abnormalities

open access: yesAdvanced Science, EarlyView.
This study identifies endothelial KDM5A as a key regulator of aging. KDM5A deficiency accelerates aging by enhancing H3K4me3‐mediated FABP4 expression, disrupting fatty acid metabolism, and promoting multi‐organ senescence. KDM5A restoration or FABP4 inhibition reverses these adverse effects and extends lifespan, positioning the KDM5A/FABP4 axis as a ...
Rifeng Gao   +21 more
wiley   +1 more source

Spatio‐Temporal Proteomic Landscape Reveals Early Warning Signals of Esophageal Squamous Cell Carcinoma Progression

open access: yesAdvanced Science, EarlyView.
This study constructs a proteomic atlas of esophageal squamous cell carcinoma (ESCC) progression using esophageal biopsy samples. It identifies moderate dysplasia as the critical turning stage and a seven‐protein panel for early detection. Functionally, GBP6 loss promotes ESCC progression via cell cycle and epithelial‐mesenchymal transition (EMT ...
Xumiao Li   +12 more
wiley   +1 more source

Student Nurses\u27 Perceptions About Caring In Early Nursing Courses [PDF]

open access: yes, 2009
This descriptive study explored students\u27 perceptions of caring at the end of their first nursing courses by identifying the caring behaviors they agreed were most important.
Roman, Rosa
core   +1 more source

Label‐Free Leukocyte Biophysical Profiling Using Impedance‐Deformability Cytometry for Rapid Cardiovascular Risk Stratification

open access: yesAdvanced Science, EarlyView.
This study presents an impedance‐based single‐cell profiling platform that quantifies the electrical and mechanical properties of neutrophils across in vitro, in vivo, and clinical samples. The approach reveals distinct biophysical alterations associated with type 2 diabetes (T2DM) and cardiovascular complications, suggesting its potential utility for ...
Linwei He   +13 more
wiley   +1 more source

English Language Acculturation and Academic Achievement Among Junior Year Nursing Students [PDF]

open access: yes, 2009
Efforts to alleviate the current nursing shortage have focused on recruitment and retention of diverse nursing students. Language acculturation has been identified in the literature as one predictor of academic achievement (Salamonson et al, 2008 ...
Lukrich, Leah
core   +1 more source

GOT1 Inhibition Induces Extracellular Matrix Remodeling in Pancreatic Cancer

open access: yesAdvanced Science, EarlyView.
Using tumor tissue engineering, we recreated pancreatic cancer and found that inhibiting glutamic‐oxaloacetic transaminase 1 (GOT1) induces extracellular matrix remodeling and secretome rewiring, as well as promotes cell death. ABSTRACT Pancreatic cancer cells rely on glutamine to sustain their survival in the stiff and poorly vascularized tumor ...
Rodrigo Curvello   +10 more
wiley   +1 more source

A New Leadership Development Model for Nursing Education [PDF]

open access: yes, 2019
Background Leadership competency is required throughout nursing. Students have difficulty understanding leadership as integral to education and practice. A consistent framework for nursing leadership education, strong scholarship and an evidence base are
Miles, Jane M., Scott, Elaine S.
core   +1 more source

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