Results 41 to 50 of about 10,780,645 (328)
Introduction and purpose: Drug poisoning is one of the more common reasons for patients being hospitalized in toxicology wards. The wide availability and ease of obtaining a wide variety of drugs and supplements are the cause of adverse reactions ...
Marlena Zając+4 more
doaj +1 more source
FoxO1 signaling in B cell malignancies and its therapeutic targeting
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac+3 more
wiley +1 more source
Abstracts from the Tenth European Students’ Conference of the Charité
N ...
European Students Conference of the Charité
doaj +1 more source
Öz: Yeni Uygur Türkçesi, Türk dili tarihi içerisinde kesintisiz olarak yazı dili olarak kullanılan Eski Uygur Türkçesinin tarihı̇ seyri içerisinde bugünkü durumuna evrilen bir yazı dilidir. Birçok ağızın etkisiyle oluşmuş ve tarihi seyri içerisinde son doksan yılda birkaç kez alfabe değişikliğine maruz kalmıştır.
openaire +1 more source
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Making tau amyloid models in vitro: a crucial and underestimated challenge
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Ground Water Contamination [PDF]
This detailed discussion explains that most ground water contamination is the result of human activity, and that several laws have been passed with an aim to minimize effects.
core +1 more source
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
How Much Water Do You Use? [PDF]
This activity is designed to make students aware of how much water individuals and families use on a weekly basis. They will analyze their family's water use with a focus on ways to reduce consumption. Students conduct the survey at home for a full week.
core +1 more source
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro+2 more
wiley +1 more source