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In this activity students assume the role of water system designers. They have been asked to go to a small town to design a new public water supply system. They must decide how to link all the homes and businesses to the water source so that everyone can
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Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The Case of the Mysterious Renters [PDF]
This activity will help students to identify ways in which water is used, determine how much water families use each day, recognize the importance of conserving water, and determine ways in which water can be conserved.
core
The field projects at this site give students an opportunity to investigate a number of wetland characteristics firsthand: surveying wetland vegetation, soils, water quality and wildlife; documenting the wetland from an artist's perspective ...
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FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Provision for students with learning difficulties in general colleges of further education - have we been going round in circles? [PDF]
This is a PDF version of an article published in British journal of special education© 2006. The definitive version is available at www.blackwell-synergy.com.This article discusses the current situation for students with severe learning difficulties in ...
Ainley +31 more
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FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Estimating risk attitudes in conventional and artefactual lab experiments [PDF]
We elicit risk preferences from student subjects and subjects drawn from the general population, using the multiple price list method devised by Holt and and Laury (2002).
Andreas Drichoutis, Phoebe Koundouri
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FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source