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Traditional student support services offered by universities are broad and varied; however, many of these fall under either student or academic affairs and are located centrally on campus. Offering a decentralized, college-specific model of student support and retention that partners with both academic and student affairs allows for a holistic ...
Shannon Collier-Tenison +1 more
openaire +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Understanding the success factors of MOOCs' retention intention: A Necessary Condition Analysis.
This paper seeks to explore the influence of success factors, specifically motivation and course quality, on MOOC retention intention. Going beyond a mere examination of these motivational and quality factors, the study investigates students' motivation,
Zhang Huacui +3 more
doaj +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Retention of physiology knowledge among medical students in basic science: a cross-sectional study
Background Medical educationists are concerned that the retention of basic science concepts weakens beyond the early years of medical programs, with clinicians rarely using basic sciences in clinical practice.
Mohammad Khaksari Hadad +3 more
doaj +1 more source
The Effect of Grade Retention on High School Completion [PDF]
Low-achieving students in many school districts are retained in a grade in order to allow them to gain the academic or social skills that teachers believe are necessary to succeed academically. This practice is highly controversial, with many researchers
Brian Jacob, Lars Lefgren
core
School Counselors\u27 Perceptions about lnterventions for At-Risk Students Including Grade Retention: Implications for School Leaders [PDF]
The term at-risk is used by educators and policymakers to describe a wide variety of students who struggle in schools (Kronholz, 2011). Factors associated with labeling students at-risk include minority status, poverty, language difficulties, low school ...
Bruce, Mary Alice +2 more
core +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Statistics reveal that while the number of Indigenous students enrolled in higher education has more than doubled from 1988 to 1993, most of the increases have occurred in education and the arts with Aboriginal and Torres Strait Islander students being ...
Sally Farrington +2 more
doaj

