Results 151 to 160 of about 67,735,822 (341)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Ethnic Studies Newsletter Vol. 2 No. 1

open access: yes, 1981
Six page newsletter from the Ethnic Studies department dated November 1981. Newsletter is Volume 2, Number 1. Newsletter includes feature on Ramón Chacón, visiting scholars, research projects, the Race Desegregation Training Institute, African Institute ...
Ethnic Studies Department;
core  

New PhDs in Sindhi Studies: 2019-2020

open access: yes, 2020
The last few years have been very productive in terms of Sindhi studies. Below, four summaries reflect on the dynamics of this field, but also the diversity of approaches. Mustafa Ahmad Khan Making Them Look the Other Way!
Asian Studies
core  

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Ethnic Studies Newsletter Vol. 5 No. 2

open access: yes, 1985
Six page newsletter from the Ethnic Studies department dated Winter 1985. Newsletter is Volume 5, Number 2 and is February: Celebrating Black History.
Ethnic Studies Department;
core  

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

open access: yesFEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Ethnic Studies Newsletter Vol. 2 No. 3

open access: yes, 1982
Three page March Supplement to the newsletter released by the Ethnic Studies department dated March 1982. Newsletter is Volume 2, Number 3. Newsletter includes Feature on Dr. George Carter; visit from Dr.
Ethnic Studies Department;
core  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Ethnic Studies Newsletter Vol. 1 No. 3

open access: yes, 1981
Six page newsletter from the Ethnic Studies department dated February 1981. Newsletter is Volume 1, Number 3. Newsletter includes piece titled A Black Woman's Perspective; Feature on Project 50; News Items including Racism in Sports Symposium, Evening of
Ethnic Studies Department;
core  

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