Results 221 to 230 of about 43,288,830 (344)

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

News : Special: Otmar Issing / Center for Financial Studies [PDF]

, 2006
Center for Financial Studies
core  

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Investigating Supervisory Feedback Practices and their Impact on International Research Student's Thesis Development: A Case Study

, 2014
Hazita Azman, Nor Fariza Mohd Nor, Nor Fariza Mohd Nor, Hnan Omar Mohamed Aghwela   +3 more
openalex   +1 more source

Estimated adherence to the Dapivirine Vaginal Ring and its associated factors among African women: A systematic review and meta-analysis. [PDF]

PLOS Glob Public Health
Dine RD, Muraca GM, Sadeghirad B, Couban R, Nyambi A, Silva J, Mbuagbaw L.   +6 more
europepmc   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

The influence of incentives and instructions on behaviour in driving simulator studies

, 2019
Catherine Harvey, Gary Burnett
openalex   +2 more sources

News : 1/03 / Center for Financial Studies [PDF]

, 2003
Center for Financial Studies
core  

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Clinical Studies of 133 Cases of Major Salivary Gland Tumors

, 2006
Yosuke Nakashimo, Sachio Takeno, Rika Osada, Hidemasa Ishii, Katsuhiro Hirakawa, Koji Yajin   +5 more
openalex   +2 more sources