Results 91 to 100 of about 2,248,033 (266)

Bullying victimization and mental health before and during the COVID-19 pandemic

open access: yesFrontiers in Child and Adolescent Psychiatry
IntroductionBullying victimization is associated with numerous mental health difficulties yet studies from early in the COVID-19 pandemic revealed significant decreases in bullying victimization but significant increases in mental health difficulties for
Ann H. Farrell   +4 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

The Catholic Religion and Its Influence on Maltese Trans Students: Sociological and Critical Anticolonial Implications for Educational Inclusion

open access: yesReligions
This study examines the schooling experiences of transgender students in Malta within the broader historical and sociocultural influence of the Catholic religion, focusing on how religious discourse shapes processes of inclusion and exclusion. Drawing on
Manuel J. Ellul
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

COVID-19 Post-Pandemic Adaptation and Resilience: A Cross-Cultural Study of China and Canada

open access: yesCOVID
The COVID-19 pandemic altered individuals’ worldviews. This study examined how cultural values shaped the ways students navigated stress and adapted after the COVID-19 pandemic.
Sarah-Mei Chen   +6 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Measuring Children’s Computational Thinking and Problem-Solving in a Block-Based Programming Game

open access: yesEducation Sciences
Computational thinking (CT) in young children (K to three) has been of much interest among educational researchers due to the applicability of CT to solving problems in daily life and various academic disciplines.
Kayla Teng, Gregory K. W. K. Chung
doaj   +1 more source

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