MiR‐513a promotes human erythroid differentiation by modulating c‐Jun
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim +11 more
wiley +1 more source
The effect of nutrition education interventions on dialysis patients' outcomes: a systematic review and meta-analysis. [PDF]
Sarmadi S, Sanaie N, Zare-Kaseb A.
europepmc +1 more source
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao +3 more
wiley +1 more source
Clozapine prescribing in treatment-resistant schizophrenia - an updated systematic literature review of barriers and facilitators among clinicians. [PDF]
Nolan S, Sahm LJ, Fitzgerald I.
europepmc +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Patient-centred educational interventions for assessing and managing cancer-related pain relevant to minority ethnic populations: A mixed-methods systematic review. [PDF]
Dehpour T +4 more
europepmc +1 more source
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley +1 more source
Retuning the Premedical Compass in American Programs Worldwide: Scoping Review.
Chouairy ME +4 more
europepmc +1 more source
Knowledge and perception of dementia risk and protective factors: a systematic review and meta-analysis. [PDF]
Sambou ML +10 more
europepmc +1 more source
Educational performance on a global educational marketplace: Comparative study
Nowadays, while considering the educational issues and the discussions and debates concerning the education, "knowledge society" has become the inevitable phrase. The knowledge and the knowledge society is a topic discussed nowadays more than ever, but it unfortunately does not mean that the knowledge gained value in society. On the question of whether
openaire +1 more source

