Results 241 to 250 of about 1,425,532 (305)

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Acceptability and adoption of a multiparameter point-of-care testing (POCT) device in primary healthcare for non-communicable diseases in resourced-limited communities in Peru. [PDF]

BMJ Open
Huayanay-Espinoza CA, Morán D, Albitres-Flores L, Bernabe-Ortiz A, Cahuana-Hurtado L, Vetter B, Safary E, Lazo-Porras M.   +7 more
europepmc   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Competence network inflammatory bowel diseases in Germany: 25 years of interdisciplinary and cross-sectoral research and knowledge transfer across all levels of IBD care. [PDF]

Ther Adv Gastroenterol
Bokemeyer B, Plachta-Danielzik S, Helwig U, Beuchert P, Schreiber S.   +4 more
europepmc   +1 more source

Centre for European Policy Studies [PDF]

, 2019
openaire   +1 more source

A National Survey of Paediatric Turner Syndrome Services in the UK: Current Practice and Variability in Care. [PDF]

Horm Res Paediatr
Law JM, Amin N, Ferguson EC, Idkowiak J, Howard SR, Katugampola H, Krone NP.   +6 more
europepmc   +1 more source

CELEBRATE Feeding: Impacts of a responsive feeding behaviour change coaching intervention in child care settings. [PDF]

J Nutr Sci
Campbell JE, Rossiter M, Young M, Caldwell S, Levin O, Mann L, Ward Chiasson S, McIsaac JD.   +7 more
europepmc   +1 more source

A practical tip for estimating skeletal maturation in children aged < 3 years using humeral ossification on chest radiographs: A retrospective study. [PDF]

Eur J Pediatr
Tsuru T, Inoue S, Edo H, Suzuki S, Imai K, Nozaki T, Shinmoto H.   +6 more
europepmc   +1 more source

Predicting outcomes in selective fetal growth restriction of monoChOrioNic Twins: an inteRnAtional observational cohort STudy protocol (CONTRAST study). [PDF]

BMJ Open
Noll A, Javinani A, Slaghekke F, Haak MC, van Klink J, Van der Meeren L, Lopriore E, Russo F, Aertsen M, Shamshirsaz A, Shinar S, Bennasar M, Tiblad E, Herling L, Lewi L, Verweij EJ, CONTRAST Study Group.   +16 more
europepmc   +1 more source

Protecting the recurrent laryngeal nerve: NerveTrend <i>vs.</i> NerveAssure in thyroid surgery. [PDF]

Gland Surg
Pinto D, Parameswaran R.
europepmc   +1 more source