Results 161 to 170 of about 3,288,415 (258)

Nutritional prehabilitation in head and neck cancer patients (PreHead) - A randomized controlled trial study protocol. [PDF]

PLoS One
Sijbrands D, Gort-van Dijk D, de Visscher SAHJ, van der Hoorn A, Steenbakkers RJHM, Jager-Wittenaar H, de Bock GH, Zwart AT, Halmos GB, Wegner I.   +9 more
europepmc   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Social and physical activity as rehabilitation for preschool kids with cancer-study protocol for a randomized controlled trial. [PDF]

Front Pediatr
Pouplier A, Fridh MK, Schmidt-Andersen P, Hoffmann M, Winther H, Christensen J, Larsen HB.   +6 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Evaluating the effectiveness and impact of the 'HSE Spark' Innovation Programme: a qualitative study protocol. [PDF]

BMJ Open
Kessie T, Ryan L, Howard M, Heffernan C, Hyland Reilly L, Gormly J.   +5 more
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Weaning from invasive ventilation with levosimendan (WEANLESS): study protocol for a multicentre randomised clinical trial. [PDF]

BMJ Open
De Leijer E, Hofma C, Serpa Neto A, Hunfeld NGM, Schultz MJ, Doorduin J, Heunks L.   +6 more
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

The benefits and costs of domiciliary care: a study protocol for evaluating the cost-effectiveness of domiciliary care in England. [PDF]

BMJ Open
Vadean F, Mamolis G, Rand S, Gousia K, Teo H, Birch S, Alvarez Nishio A, Towers AM, Allan S, Darton R, Gregory F, Lambert C, Fenton W, Davison S, Roberts A, Nizalova O.   +15 more
europepmc   +1 more source