Results 191 to 200 of about 3,288,415 (258)

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

Dose Recommendations for Drugs in Patients With Liver Cirrhosis (The ALIVe Study): Protocol for a Multiphase Validation and Consensus Study. [PDF]

JMIR Res Protoc
Karsten Dafonte K, Lutz P, Jansen C, Strassburg CP, Németh R, Hartmann G, Jaehde U, Coenen M.   +7 more
europepmc   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

Meaning-Centered Psychotherapy for Cancer Caregivers: Study protocol of a randomized controlled trial. [PDF]

Trials
Applebaum AJ, Walsh LE, Zaider T, Baser RE, Loschiavo MJ, Breitbart WS, Lichtenthal WG.   +6 more
europepmc   +1 more source

Protocol changes to the TRIUMPH study

American Heart Journal, 2017
openaire   +3 more sources

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Correction: First-line treatment of camrelizumab combined with chemotherapy in advanced gastroenteropancreatic neuroendocrine carcinoma: study protocol for a prospective, multicenter, phase II study

Frontiers in Oncology
Xiaofen Li, Qing Ma, Chen Chang, Hao Li, Dan Cao   +4 more
doaj   +1 more source

Research priorities in pleural disease: study protocol for a joint patient-provider Delphi consensus statement. [PDF]

BMJ Open Respir Res
Shaw JA, Milne A, Mei F, Bodtger U, Walker SP.   +4 more
europepmc   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Endovascular Acute Stroke Intervention-Tandem Occlusion (EASI-TOC) study: protocol and rationale. [PDF]

Eur Stroke J
Mendes GN, Jacquin G, Iancu D, Roy D, Yu M, Bodson-Clermont P, Fahmi I, Ahmed SU, Almekhlafi M, Buck B, Camden MC, Catanese L, Diestro D, Fahed R, Field TS, Guest W, Hawkes C, Hill MD, Kelly ME, Kim CN, Legault C, Milot G, Moreau F, Muccilli A, Rempel J, Shamy M, Singh RJ, Van Adel BA, Volders D, Shankar J, Singh N, Stapf C, Poppe AY.   +32 more
europepmc   +1 more source