Results 21 to 30 of about 36,154,612 (288)

Microinjection of β-glucan Into Larval Zebrafish (Danio rerio) for the Assessment of a Trained-Like Immunity Phenotype

, 2023
The innate immune system can remember previous inflammatory insults, enabling long-term heightened responsiveness to secondary immune challenges in a process termed "trained immunity." Trained innate immune cells undergo metabolic and epigenetic ...
Hall, Christopher J, Darroch, Hannah, Astin, Jonathan W   +2 more
core   +1 more source

Efficacy, safety and mechanism of Honghua Xiaoyao Pill in the treatment of peri-menopausal syndrome: A study protocol for a randomized controlled trial

Frontiers in Pharmacology, 2022
Background: Peri-menopausal syndrome (PMPS) has a high incidence rate and seriously affects the physical and mental health of women. Honghua Xiaoyao Pill (HHXYP) is a Chinese patent medicine, which has been reported to be used to treat PMPS.
Xiao Wu, Lishan Zhou, Haoxu Dong, Man Tian, Shiqin Liu, Xiaohu Xu   +5 more
doaj   +1 more source

Ensifer-mediated Arabidopsis thaliana Root Transformation (E-ART): A Protocol to Analyse the Factors that Support Ensifer-mediated Transformation (EMT) of Plant Cells [PDF]

, 2017
peer-reviewedEnsifer adhaerens OV14, a soil borne alpha-proteobacteria of the Rhizobiaceae family, fortifies the novel plant transformation technology platform termed ‘Ensifer-mediated transformation’ (EMT).
Fiona Doohan, Ewen Mullins, Rathore, Deeraj Singh, Doohan, Fiona, Mullins, Ewen, Dheeraj Rathore   +5 more
core   +1 more source

Cell-based assay for recruitment of DDR1 to collagen-coated beads [PDF]

, 2019
The discoidin domain receptors, DDR1 and DDR2, are key signaling receptors for the extracellular matrix protein collagen. The interactions of cells with collagen are difficult to study because of the difficulty to obtain native collagen fibers for in ...
Leitinger, Birgit, Juskaite, Victoria
core   +1 more source

Study Protocol for Evaluation of an Extended Maintenance Intervention on Life Satisfaction and BMI Among 7–14-Year-Old Children Following a Stay at a Residential Health Camp in Denmark

Frontiers in Public Health, 2021
Background: It is challenging to maintain effects of public health interventions. For residential health camps benefits often disappear as the child returns home. Furthermore, long-term effects are often not measured or reported.
Mette Juul Kristoffersen, Susan Ishøy Michelsen, Mette Rasmussen, Pernille Due, Lau Caspar Thygesen, Rikke Fredenslund Krølner   +5 more
doaj   +1 more source

Standardized Protocol Items Recommendations for Observational Studies (SPIROS) for Observational Study Protocol Reporting Guidelines: Protocol for a Delphi Study [PDF]

JMIR Research Protocols, 2020
Background Approximately 90% of currently published clinical and public health research is in the form of observational studies. Having a detailed and registered study protocol prior to data collection is important in any empirical study.
Raman Mahajan, Sakib Burza, Lex M Bouter, Klaas Sijtsma, André Knottnerus, Jos Kleijnen, Peter Van Dael, Maurice P Zeegers   +7 more
openaire   +3 more sources

Identification of Factors in Regulating a Protein Ubiquitination by Immunoprecipitation: a Case Study of TRF2 on Human REST4 Ubiquitination. [PDF]

, 2015
Ubiquitination is the first step of the ubiquitin-proteasome pathway that regulates cells for their homeostatic functions and is an enzymatic, protein post-translational modification process in which ubiquitin is transferred to a target protein substrate
Cui, W, Ovando-Roche, P
core   +1 more source

Randomized, Double-Blind, Placebo-Controlled, Phase I, Dose- Escalation Study to Evaluate the Tolerance, Pharmacokinetics, Pharmacodynamics and Immunogenicity of PEGylated Urate Oxidase for Injection in Healthy Adults and Hyperuricemia Volunteers: Study Protocol

Diabetes, Metabolic Syndrome and Obesity, 2023
Feifei Sun,1,* Chenjing Wang,1,* Yi Xu,1 Pingping Lin,1 Yaozhong Cao,2 Jiahui Zhang,3 Xin Li,1 Xin Jiang,1 Yao Fu,1 Yu Cao1 1Clinical Trials Center, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, People’s Republic of China ...
Sun F, Wang C, Xu Y, Lin P, Cao Y, Zhang J, Li X, Jiang X, Fu Y, Cao Y   +9 more
doaj  

Effects of cannabis regulation in Switzerland: Study protocol of a randomized controlled trial

Frontiers in Psychiatry, 2023
BackgroundCannabis is the most widely used illicit substance. Various countries have legalized cannabis for recreational use. Evidence on the health effects of cannabis regulation remains unclear and is mainly based on observational studies.
Lavinia Baltes-Flueckiger, Regine Steinauer, Maximilian Meyer, Marc Vogel, Marc Walter, Marc Walter   +5 more
doaj   +1 more source

The LIFEwithIBD Intervention: Study Protocol for a Randomized Controlled Trial of a Face-to-Face Acceptance and Commitment Therapy and Compassion-Based Intervention Tailored to People With Inflammatory Bowel Disease

Frontiers in Psychiatry, 2021
Background: There is ample evidence of the high mental health burden caused by Inflammatory Bowel Disease (IBD). Several constructs such as experiential avoidance, cognitive fusion, shame, and self-criticism have recently emerged as potential ...
Inês A. Trindade, Inês A. Trindade, Joana Pereira, Ana Galhardo, Ana Galhardo, Nuno B. Ferreira, Paola Lucena-Santos, Sérgio A. Carvalho, Sérgio A. Carvalho, Sara Oliveira, David Skvarc, Bárbara S. Rocha, Francisco Portela, Cláudia Ferreira   +13 more
doaj   +1 more source