Results 81 to 90 of about 1,077,623 (316)
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
GOTHIC LANGUAGE STYLE IN CHARLOTTE BRONTE’S JANE EYRE (A Stylistics Approach) [PDF]
Hemy Suzana. C0305033. 2010. Gothic Language Style in Charlotte Bronte’s Jane Eyre. Thesis. English Department, Faculty of Letters and Fine Arts, Sebelas Maret University, Surakarta.
SUZANA, HEMY
core
Background: Hypertension during pregnancy is one of the leading causes of maternal morbidity and mortality. Rosella flower infused-water, rich in bioactive compounds such as flavonoids and polyphenols, have been shown to lower blood pressure safely ...
dewita rahmatul amin +1 more
doaj +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Style-Based architectural reconfigurations
We introduce Architectural Design Rewriting (ADR), an approach to the design of reconfigurable software architectures whose key features are: (i) rule-based approach (over graphs); (ii) hierarchical design; (iii) algebraic presentation; and (iv ...
Lluch-Lafuente, Alberto +7 more
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The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Adaptive Hypermedia made simple using HTML/XML Style Sheet Selectors [PDF]
This paper addresses enhancing HTML and XML with adaptation functionalities. The approach consists in using the path selectors of the HTML and XML style sheet languages CSS and XSLT for expressing content and navigation adaptation. Thus, the necessary
Kraus, Michael +3 more
core +1 more source
Giacomo Prando explains how his experience as an editor helped him broaden his horizons as a scientist.
openaire +3 more sources

