Results 161 to 170 of about 3,164,616 (286)

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

open access: yesMolecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba   +5 more
wiley   +1 more source

LEAST: "Local" text-conditioned image style transfer [PDF]

open access: yes
Text-conditioned style transfer enables users to communicate their desired artistic styles through text descriptions, offering a new and expressive means of achieving stylization.
Singh, Silky   +3 more
core  

Music2Fail: Transfer Music to Failed Recorder Style

open access: yes
The goal of music style transfer is to convert a music performance by one instrument into another while keeping the musical contents unchanged. In this paper, we investigate another style transfer scenario called ``failed-music style transfer\u27\u27 ...
Chao, Kin-Fong   +5 more
core   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

open access: yesMolecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir   +9 more
wiley   +1 more source

Style Transfer-assisted Deep Learning Method for Kidney Segmentation at Multiphase MRI. [PDF]

open access: yesRadiol Artif Intell, 2023
Guo J   +6 more
europepmc   +1 more source

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

open access: yesMolecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan   +8 more
wiley   +1 more source

Content style transfer using RAG

open access: yes
Retrieval-Augmented Generation (RAG) pipelines are traditionally used to augmentLarge Language Models (LLMs) with external, factual knowledge. However, theirpotential applications in Content Style Transfer , the process of preserving a message’s meaning ...

core  

The multifaceted roles of lysosomes in cancer

open access: yesMolecular Oncology, EarlyView.
Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley   +1 more source

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