Results 41 to 50 of about 26,633 (306)

Pemodelan 3D Lapisan Dasar Laut Dan Identifikasi Ketebalan Sedimen Berdasarkan Kombinasi Data Pengukuran Sub-Bottom Profiler Dan Single Beam Echosounder (Studi Kasus: Alur Akses Timur Surabaya)

Journal of Geospatial Information Science and Engineering, 2021
Pelabuhan merupakan salah satu fasilitas umum yang memiliki peran penting dalam keselamatan navigasi pelayaran. Shipping yang aman harus didukung dengan pemantauan dan pemeliharaan secara berkala untuk mendapatkan informasi terkini tentang kedalaman ...
Windy Hapsari, Bambang Kun Cahyono
doaj   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Pre-rig mobilization hazard evaluation in offshore oil and gas prospect drilling: A case study of TM field, offshore Niger Delta

Energy Geoscience, 2023
TM Field, located offshore Niger Delta in the Gulf of Guinea (Nigeria), has been evaluated for potential drilling hazards prior to the drilling of a proposed oil well.
Oluwatimilehin B. Balogun, Olajumoke C. Akintokewa   +1 more
doaj   +1 more source

Mycophenolic acid (MPA) modulates host cellular autophagy progression in sub genomic dengue virus-2 replicon cells [PDF]

, 2019
Cellular autophagy (Macrophagy) is a self-degradative process, executed through the network of autophagy associated genes (ATGs) encoded proteins. Both in vitro and in vivo studies suggest that dengue virus (DENV) induces autophagy and supports the viral
Dungdung, Ranjeet, Manchala, Nageswar Reddy, Pilankatta, Rajendra, Trivedi, Pankaj, Unniyampurath, Unnikrishnan   +4 more
core   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Specific features of the upper sedimentary cover and slump structures in the NW Pacific and the Bering Sea based on seismoacoustic profiling data [PDF]

Вестник Камчатской региональной ассоциации "Учебно-научный центр". Серия: Науки о Земле, 2019
The authors studied geology-geophysical data that had been obtained during German RV «Sonne» Cruise in NW Pacific organized in frames of the Russian-German Project KALMAR («Kurile-Kamchatka and Aleutian Marginal sea-island arc systems: geodynamic and ...
Tsukanov, N.V., Dozorova, K.A., Gaedicke, C.   +2 more
doaj   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

An Experiment of the Actual Vertical Resolution of the Sub-bottom Profiler in an Anechoic Tank

Archives of Acoustics, 2019
Sub-bottom profiler (SBP) is an acoustic instrument commonly used to survey underwater shallow geological structure and embedded objects whose most important performance parameter is the actual vertical resolution.
Fangqi WANG, Lifeng DONG, Jisheng DING, Xinghua ZHOU, Changfei TAO, Xubo LIN, Guanhui LIANG   +6 more
doaj   +1 more source

First AUV and ROV investigation of seismogenic faults in the Alboran Sea (Western Meditarranean) [PDF]

, 2016
In May-June 2015 we carried out the SHAKE cruise on board the RV “Sarmiento de Gamboa” the first in situ investigation using state-of-the-art underwater vehicles, the AUVs “AsterX” and “IdefX” (IFREMER, France) and the ROV “Max Rover” (HCMR, Greece ...
Bartolomé de la Peña, Rafael, Costa, Sergio, Dañobeitia, Juan José, Díez, Susana, Gràcia, Eulàlia, Lo Iacono, Claudio, Perea, Hector, Placaud, Xavier, Rodríguez, Pablo, Smith, Chris, Sánchez, Héctor   +10 more
core  

The role of intratidal oscillations in sediment resuspension in a diurnal, partially mixed estuary [PDF]

, 2010
Using detailed observations of the mean and turbulent properties of flow, salinity and turbidity that spanned 2001/02, we examined the physical mechanisms underpinning sediment resuspension in the low-energy Swan River estuary, Western Australia. In this
Aubrey, Becker, Blanton, C. B. Pattiaratchi, Cooper, D. P. Hamilton, Deines, Dyer, Dyer, Etemad-Shahidi, Hamilton, Hamilton, Hodgkin, Hoitink, Hoitink, Imberger, J. M. O'Callaghan, Kim, Lemckert, Levasseur, Lorke, Mitchener, Nepf, O'Callaghan, O'Callaghan, Peters, Peters, Pugh, Pugh, Ranasinghe, Ridd, Simpson, Spencer, Stacey, Stevens, Stokes, Tedford, Tennekes, Uncles, van de Kreeke, van der Ham, van Maren, van Rijn, Weisberg, Whitehouse, Woodworth, Wright   +46 more
core   +2 more sources