Results 51 to 60 of about 26,633 (306)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

A Complex of Marine Geophysical Methods for Studying Gas Emission Process on the Arctic Shelf

open access: yesSensors, 2023
The Russian sector of the arctic shelf is the longest in the world. Quite a lot of places of massive discharge of bubble methane from the seabed into the water column and further into the atmosphere were found there.
Artem A. Krylov   +18 more
doaj   +1 more source

4. Wochenbericht M77/1 [PDF]

open access: yes, 2008
Im Pazifischen Ozean erstreckt sich westlich von Peru und Ecuador ein riesiges Gebiet, in dem lebenswichtiger Sauerstoff Mangelware ist. Dieses Gebiet ist Ziel der Expedition „M77“, zu der das deutsche Forschungsschiff METEOR am 22. Oktober 2008 ausläuft.
Pfannkuche, Olaf
core  

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

RV Sonne Cruise 200, 11 Jan-11 Mar 2009. Jakarta - Jakarta [PDF]

open access: yes, 2008
All plate boundaries are divided into segments - pieces of fault that are distinct from oneanother, either separated by gaps or with different orientations.
Dayuf Jusuf, M., McNeill, L.C.
core   +1 more source

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon   +12 more
wiley   +1 more source

Hydrographic Drone Non-Invasive Underwater Investigations: New Archaeological Discoveries in Valle Fossa di Porto (Comacchio—FE, Italy)

open access: yesHeritage, 2023
During forensic archaeological research conducted in 2021 in the Comacchio Lagoon (FE), we detected new data concerning the ancient local hydrography to the west of Argine Agosta, an ancient bank, in Valle Fossa di Porto.
Giovanna Bucci
doaj   +1 more source

Oceanus. [PDF]

open access: yes, 1995
v.
Woods Hole Oceanographic Institution.
core   +1 more source

Subtidal water level variation controlled by river flow and tides [PDF]

open access: yes, 2009
Subtidal water level dynamics in the Berau river, East Kalimantan, Indonesia, feature a pronounced fortnightly variation. The daily mean water levels at a station about 60 km from the sea are 0.2–0.6 m higher during spring tide than during neap tide.
Buschman, F.A.   +3 more
core   +2 more sources

Home - About - Disclaimer - Privacy