Results 51 to 60 of about 39,415 (259)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Level of stress among schoolteachers of a school in South Delhi, India

CHRISMED Journal of Health and Research, 2019
Background: Modernization and increasing level of competition in day to day life has increased the expectations from teachers. Objective: To describe the level of stress and its associated factors among teachers using Teacher's stress inventory in a ...
Mamta Parashar, Deeksha Ellawadi, Mitasha Singh, Ram Chander Jiloha   +3 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Provider implicit and explicit bias in person-centered maternity care: a cross-sectional study with maternity providers in Northern Ghana

BMC Health Services Research, 2023
Background Person-centered maternity care (PCMC) has become a priority in the global health discourse on quality of care due to the high prevalence of disrespectful and lack of responsive care during facility-based childbirth.
Patience A. Afulani, Jaffer Okiring, Raymond A. Aborigo, Jerry John Nutor, Irene Kuwolamo, John Baptist K. Dorzie, Sierra Semko, Jason A. Okonofua, Wendy Berry Mendes   +8 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Differential migration in Chesapeake Bay striped bass.

PLoS ONE, 2020
Differential migration-increased migration propensity with increasing individual size-is common in migratory species. Like other forms of partial migration, it provides spatial buffering against regional differences in habitat quality and sources of ...
David H Secor, Michael H P O'Brien, Benjamin I Gahagan, J Carter Watterson, Dewayne A Fox   +4 more
doaj   +1 more source

A note on the cluster set of the law of the iterated logarithm under sub-linear expectations

Probability, Uncertainty and Quantitative Risk, 2022
arXiv admin note: text overlap with arXiv:2109.13083, arXiv:2103 ...
openaire   +2 more sources

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Research on a Damage Assessment Method for Concrete Components Based on Material Damage

Buildings
With the popularization of the concept of seismic performance-based design, the correct and quantitative evaluation of post-earthquake damage to structural components has become a research focus.
Hongjun Wang, Xiaodan Ren, Zhi Li, Mingsheng Tang   +3 more
doaj   +1 more source