Results 111 to 120 of about 13,073,871 (296)
FEBS Letters, EarlyView.Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
, 2012 This chapter discusses South Asian subaltern studies as well as their adaptation by Latin Americanist historian Florencia Mallon and by the Latin American Subaltern Studies Group.
Walter D. Mignolo
core +1 more source
The ubiquitin system in normal and infected germinal center B cells
FEBS Letters, EarlyView.The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
Provincializing Europe, Twenty-five Years On: Retrospect and Reconsideration
Ler HistóriaThis essay revisits Provincializing Europe twenty-five years after its publication, reflecting on its intellectual origins, theoretical interventions, and critical reception.
Dipesh Chakrabarty
doaj +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
The production, transnational circulation and re articulation of the ‘subaltern question’ from Gramsci to Postcolonial studies [PDF]
The ‘subaltern question’ cuts across various intellectual endeavours –from Gramsci’s Prison Notebooks in the 1930s, through the Italian folklore debates and British ‘history from below’ during the 1950s-1960s, to Subaltern Studies in the 1980s and, more ...
Piu, Piermarco
core
'Becoming' Subalterns: Writing and Scribbling in Early Modern Prisons
Journal of Early Modern StudiesAccording to Spivak, the subaltern was ‘removed from all lines of social mobility’ (2004, 531), deprived of their capacity to speak and excluded from representation in both political and aesthetic senses.
Anna Clara Basilicò
doaj +1 more source
Recruitmentology and the politics of consent in clinical research. [PDF]
Lancet, 2023 Sabet C, Bajaj SS, Stanford FC.
europepmc +1 more source
Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source