Results 151 to 160 of about 736,886 (292)

Astragaloside IV and Ferroptosis Modulation in Pathological Cardiac Hypertrophy: Current Evidence, an Integrative Hypothesis, and Future Directions

Pharmacology Research &Perspectives, Volume 14, Issue 6, December 2026.
ABSTRACT Pathological cardiac hypertrophy is initially an adaptive response to sustained mechanical, neurohormonal, or metabolic stress; however, it can progress to fibrosis, contractile dysfunction, arrhythmia, and heart failure. Ferroptosis is a type of regulated cell death caused by iron‐dependent phospholipid peroxidation.
Pengbo Liu, Yongzhi Deng
wiley   +1 more source

Nitric oxide inhalation reduces brain damage, prevents mortality, and improves neurological outcome after subarachnoid hemorrhage by resolving early pial microvasospasms.

, 2015
Subarachnoid hemorrhage is a stroke subtype with particularly bad outcome. Recent findings suggest that constrictions of pial arterioles occurring early after hemorrhage may be responsible for cerebral ischemia and - subsequently - unfavorable outcome ...
Stover, John, Dienel, Ari, Müller, Frank, Schöller, Karsten, Thal, Serge, Heumos, Nicole, Feiler, Sergej, Friedrich, Benjamin, Plesnila, Nikolaus, Terpolilli, Nicole A, Heumos N, Dienel A, Friedrich B, Müller F, Thal S, Plesnila N, Terpolilli NA, Stover J, Feiler S, Schöller K   +19 more
core   +1 more source

Inflammatory changes in the choroid plexus following subarachnoid hemorrhage: the role of innate immune receptors and inflammatory molecules

Frontiers in Cellular Neuroscience
IntroductionThe choroid plexus is located in the cerebral ventricles. It consists of a stromal core and a single layer of cuboidal epithelial cells that forms the blood-cerebrospinal barrier.
Peter Solár, Peter Solár, Václav Brázda, Václav Brázda, Martin Bareš, Alemeh Zamani, Parisa EmamiAref, Andrea Joukal, Lucie Kubíčková, Erik Kročka, Klaudia Hašanová, Marek Joukal   +11 more
doaj   +1 more source

Neutrophil Extracellular Traps Block Fibrinolysis in Ischemic Stroke

Annals of Neurology, Volume 100, Issue 5, Page 964-978, November 2026.
Objectives Intravenous thrombolysis (IVT) failure in acute ischemic stroke (AIS) is frequent, but its causes remain elusive. We investigated whether biologically relevant intrathrombus concentrations of tissue plasminogen activator (tPA) were achieved in failed IVT and whether neutrophil extracellular traps (NETs) contributed to this therapeutic ...
Mialitiana Solo Nomenjanahary, Jean‐Philippe Desilles, Fatima Zemali, Astride Perrot, Lucas Di Meglio, Sara Zalghout, Jéromine Fasille, Jérémy Neel, Stéphane Loyau, Julien Labreuche, Marie‐Charlotte Bourrienne, Dorothée Faille, François Delvoye, Véronique Ollivier, Sébastien Dupont, Jasmina Rogozarski, Nahida Brikci‐Nigassa, Robert L. Medcalf, Nadine Ajzenberg, Mikael Mazighi, Benoît Ho‐Tin‐Noé, the compoCLOT Study Group   +21 more
wiley   +1 more source

Histopathological changes in ciliary ganglion of rabbits with subarachnoid hemorrhage

, 2005
The histopathological changes in the ciliary ganglia due to subarachnoid hemorrhage were investigated. Subarachnoid hemorrhage was produced by infusing autologous blood to the cisterna magna of rabbits.
SAHIN, O, AKYOL-SALMAN, İlknur, Aydin, Mehmet Dumlu   +2 more
core   +1 more source

Two Cases of Terson’s Syndrome

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2009
BACKGROUND AND OBJECTIVE: Subarachnoid hemorrhage due to head trauma, rupture of brain aneurysms, etc can be associated with vitreous and retinal hemorrhage and is named Terson’s syndrome and has no adverse effect on visual prognosis and survival if ...
M Nili Ahmadabadi,, B Pourmostadam, R Karkhaneh, E michaeli, A solemani   +4 more
doaj  

Non‐contrast CT Markers of Hematoma Expansion and Andexanet Response in Factor Xa Inhibitor‐Associated Intracerebral Hemorrhage: An Analysis from ANNEXa‐I Trial

Annals of Neurology, Volume 100, Issue 5, Page 979-983, November 2026.
In this post hoc analysis of the ANNEXa‐I trial (n = 434), we evaluated non‐contrast computed tomography (NCCT) markers of hematoma expansion (HE) in factor Xa inhibitor (FXai) –associated intracerebral hemorrhage (ICH). At least one NCCT marker was present in 72.1%, and HE (≥12.5 mL or ≥ 35% increase in hematoma volume) occurred in 31.8 ...
Koji Tanaka, Umberto Pensato, Mohamed Alshamrani, Aristeidis H. Katsanos, Pargol Balali, Sucharita Ray, Scott E. Kasner, Jan Beyer‐Westendorf, Danilo Toni, David J. Seiffge, Carlos Molina, David Tanne, Anna Członkowska, Arne G. Lindgren, Daniel Bereczki, Else C. Sandset, Georgios Tsivgoulis, Hanne Christensen, Jonathan M. Coutinho, Peter Verhamme, Pierre Amarenco, Robin Lemmens, Roland Veltkamp, Saskia Middeldorp, Thompson Robinson, Truman J. Milling, Wilfried Lang, Vitor Tedium‐Cruz, Mark Crowther, Lizhen Xu, Mikael Knutsson, Per Ladenvall, John W. Eikelboom, Mukul Sharma, Ashkan Shoamanesh, Andrew M. Demchuk   +35 more
wiley   +1 more source

Characteristics of Patients with Aneurysmal Subarachnoid Hemorrhage with Delayed Hospital Arrival

Neurologia Medico-Chirurgica
The timing of aneurysmal obliteration may be influenced by post-admission rebleeding rates and patient characteristics associated with delayed hospital arrival in cases of aneurysmal subarachnoid hemorrhage.
Susumu YAMAGUCHI, Kazuhiko SUYAMA, Hajime MAEDA, Yoichi MOROFUJI, Makio KAMINOGO, Takeo ANDA, Tsuyoshi IZUMO, Takayuki MATSUO, on behalf of the Nagasaki SAH Registry Study   +8 more
doaj   +1 more source

Ixodes ricinus‐Contact Phase Inhibitor Promotes Functional Recovery and Attenuates Neutrophil Associated Neuroinflammation After Experimental Intracerebral Hemorrhage

CNS Neuroscience &Therapeutics, Volume 32, Issue 11, November 2026.
Ixodes ricinus‐Contact Phase Inhibitor (Ir‐CPI), a selective FXIa/XIIa inhibitor with reported thromboinflammatory modulatory properties, improves recovery after intracerebral hemorrhage (ICH) without increasing bleeding. By targeting thromboinflammation, Ir‐CPI limits neutrophil infiltration and NET formation, reducing secondary neuronal injury. These
Stéphanie Demoulin, Annelise Letourneur, Florent Lebrun, Nicolas Violle, Denis Vivien, Valérie Pireaux   +5 more
wiley   +1 more source

Therapeutic potential of stem cells in subarachnoid hemorrhage

Neural Regeneration Research
Aneurysm rupture can result in subarachnoid hemorrhage, a condition with potentially severe consequences, such as disability and death. In the acute stage, early brain injury manifests as intracranial pressure elevation, global cerebral ischemia, acute ...
Hideki Kanamaru, Hidenori Suzuki
doaj   +1 more source