Results 71 to 80 of about 61,577 (279)

The role of ubiquitin C–terminal hydrolase (UCH‐L1) and protein S100B in differentiating patients with epileptic and psychogenic non‐epileptic seizures – Pilot study

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Psychogenic non‐epileptic seizures (PNES) are functional neurological disorders that are often misdiagnosed and treated as epileptic seizures (ES). Video‐electroencephalography (v‐EEG) is the gold standard for differentiating ES from PNES.
Biljana Dapic Ivancic   +5 more
wiley   +1 more source

Tau‐targeting nanoparticles for treatment of Alzheimer's disease

open access: yesExploration, EarlyView.
Through review of comprehensive literature and research studies, it is found that tau‐targeting nanoparticles may posit beneficial applications to AD therapy. By targeting a key molecular mechanism known to propagate AD pathogenesis, tau‐targeting nanoparticles have the potential to facilitate tau tangle clearance, promote synaptic integrity, and ...
Shreya Pawar   +3 more
wiley   +1 more source

Commentary [Decompressive craniectomy in patients with cerebral infarction due to malignant vasospasm after aneurysmal subarachnoid hemorrhage] [PDF]

open access: yes, 2012
Commentary: article "Decompressive craniectomy in patients with cerebral infarction due to malignant vasospasm after aneurysmal subarachnoid hemorrhage" on page 251 http://www.ncbi.nlm.nih.gov/pmc/articles ...
Archavlis, Eleftherios
core  

Drug delivery pathways to the central nervous system via the brain glymphatic system circumventing the blood‐brain barrier

open access: yesExploration, EarlyView.
The discovery of the glymphatic system has opened up a pathway for drug delivery to the brain by circumventing the blood‐brain barrier, which can effectively improve drug utilization. The methods of drug delivery through the glymphatic system include intrathecal injection, intranasal injection, and delivery through the meningeal lymphatic vessels.
Xiang Wang   +7 more
wiley   +1 more source

Unsupervised Acute Intracranial Hemorrhage Segmentation with Mixture Models [PDF]

open access: yesarXiv, 2021
Intracranial hemorrhage occurs when blood vessels rupture or leak within the brain tissue or elsewhere inside the skull. It can be caused by physical trauma or by various medical conditions and in many cases leads to death. The treatment must be started as soon as possible, and therefore the hemorrhage should be diagnosed accurately and quickly.
arxiv  

Bazedoxifene, a selective estrogen receptor modulator, reduces cerebral aneurysm rupture in Ovariectomized rats. [PDF]

open access: yes, 2017
BackgroundEstrogen deficiency is thought to be responsible for the higher frequency of aneurysmal subarachnoid hemorrhage in post- than premenopausal women.
Hashimoto, Tomoki   +8 more
core   +1 more source

Proteome‐Wide Mendelian Randomization Identifies Candidate Causal Proteins for Cardiovascular Diseases

open access: yesAdvanced Genetics, EarlyView.
Here, causal relations are examined between 2940 plasma proteins and 19 cardiovascular diseases (CVD) using a human genetics‐based method. 218 proteins are found whose blood levels influence CVD risks, with about half being new discoveries and largely confirmed in an independent cohort.
Chen Li   +13 more
wiley   +1 more source

Neuroprotection mediated by the Wnt/Frizzled signaling pathway in early brain injury induced by subarachnoid hemorrhage

open access: yesNeural Regeneration Research, 2019
The Wnt/Frizzled signaling pathway participates in many inflammation-linked diseases. However, the inflammatory response mediated by the Wnt/Frizzled signaling pathway in experimental subarachnoid hemorrhage has not been thoroughly investigated ...
Yang Wang   +6 more
doaj   +1 more source

Spontaneous subarachnoid haemorrhage due to coarctation of aorta and intraspinal collaterals : a rare presentation [PDF]

open access: yes, 2012
The occurrence of spontaneous subarachnoid haemorrhage (SAH) in association with coarctation of thoracic aorta and absence of intracranial aneurysm is a rare association.
Devara, Anil K.V.   +2 more
core  

Deep learning-based multiclass segmentation in aneurysmal subarachnoid hemorrhage

open access: yesFrontiers in Neurology
IntroductionRadiological scores used to assess the extent of subarachnoid hemorrhage are limited by intrarater and interrater variability and do not utilize all available information from the imaging. Image segmentation enables precise identification and
Julia Kiewitz   +14 more
doaj   +1 more source

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