Results 71 to 80 of about 736,886 (292)

Neuroprotection in Subarachnoid Hemorrhage [PDF]

Stroke, 2010
Despite advances in aneurysm ablation and the initial management of patients presenting with aneurysmal subarachnoid hemorrhage, delayed cerebral ischemia remains a significant source of morbidity. Traditionally, delayed cerebral ischemia was thought to be a result of vasospasm of the proximal intracranial vessels, and clinical trials have relied ...
Daniel T, Laskowitz, Brad J, Kolls
openaire   +2 more sources

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source

Remote Ischemic Post‐Conditioning Preserves the Neurovascular Unit by Brain‐Derived Gas6 That Drives Monocyte‐Derived Macrophage Reprogramming via Axl and Vimentin after SAH

Advanced Science, EarlyView.
Subarachnoid hemorrhage (SAH) triggers monocyte‐derived macrophage (MDM) infiltration and M1‐like polarization via Vimentin upregulation, leading to neurovascular unit disruption and cognitive dysfunction. Remote ischemic postconditioning (RIPostC) upregulates neuronal Gas6, which activates Axl on MDMs to downregulate Vimentin and drive reparative M2 ...
Yajun Zhu, Zichao Huang, Xi Rong, Xingwei Lei, Fuming Liang, Xiaoguo Li, Jiru Zhou, Yu Wang, Yifan Huang, Shuang Tang, Jianjun Zhong, Jin Yan, Hongji Deng, Chun Zeng, Zongduo Guo   +14 more
wiley   +1 more source

A case of cerebral venous sinus thrombosis presented with SAH and isolated headache

Radiology Case Reports, 2023
Cerebral venous sinus thrombosis is a rare and challenging type of stroke. Coexistence of subarachnoid hemorrhage adds complexity to the diagnostic process leading to a missed or delayed diagnosis.
Nali Ahmed, MBChB, Mohamed Ibrahim, MBChB, FRCR, MD/PhD, Dmitriy Starostin, MBChB, FRCR   +2 more
doaj   +1 more source

Stroke‐Heart Syndrome: Mechanisms, Temporal Phenotypes, and Diagnostic Reasoning

Advanced Science, EarlyView.
Stroke‐heart syndrome describes new or worsened cardiac abnormalities after acute stroke. This Review defines its clinical boundaries, traces autonomic, inflammatory, endothelial, and supply‐demand mechanisms across time, and proposes provisional phenotypes that integrate lesion location, premorbid cardiac substrate, serial biomarkers ...
Fa Lin, Jian Lyu, Yanci Liu, Zhiyuan Feng, Jie Bao, Wenxiong Song, Bingcheng Zhu, Minghao Liu, Jionghao Xue, Jiadi Weng, Jiani Zhang, Jizong Zhao, Xiaolin Chen, Bin Dong   +13 more
wiley   +1 more source

Continuous Electroencephalography Predicts Delayed Cerebral Ischemia after Subarachnoid Hemorrhage: A Prospective Study of Diagnostic Accuracy

Annals of Neurology, 2018
Delayed cerebral ischemia (DCI) is a common, disabling complication of subarachnoid hemorrhage (SAH). Preventing DCI is a key focus of neurocritical care, but interventions carry risk and cannot be applied indiscriminately. Although retrospective studies
E. Rosenthal, S. Biswal, S. Zafar, K. O'Connor, Sophia C. Bechek, A. Shenoy, Emily J. Boyle, Mouhsin M. Shafi, E. Gilmore, Brandon Foreman, N. Gaspard, T. Leslie-Mazwi, J. Rosand, Daniel B. Hoch, C. Ayata, Sydney S. Cash, Andrew J. Cole, Aman B. Patel, M. Westover   +18 more
semanticscholar   +1 more source

Animal stroke models and outcome evaluation: A review

Animal Models and Experimental Medicine, EarlyView.
Rodents are the preeminent stroke model species. Large animal models exist too, but are poorly standardized. Ischemic and hemorrhagic experimental models are available, with the intraluminal filament model being predominant. Outcomes are evaluated via quantifying subjects' sensorimotor impairment, cognitive memory faculties, degree of cellular ...
Solsa Cariba, Helen M. Atkinson, Anthony K. C. Chan   +2 more
wiley   +1 more source

Temporal muscle thickness and area with various characteristics data of the patients with aneurysmal subarachnoid hemorrhage who underwent endovascular coiling

Data in Brief, 2020
These data present the characteristics of patients with subarachnoid hemorrhage who underwent endovascular coiling. We retrospectively collected data from the medical records of Iwaki City Medical Center including physiological symptoms, laboratory data,
Masahito Katsuki, Yasuhiro Suzuki, Keiko Kunitoki, Yoshimichi Sato, Keisuke Sasaki, Shoji Mashiyama, Ryo Matsuoka, Elissa Allen, Hibiki Saimaru, Ryota Sugawara, Akinori Hotta, Teiji Tominaga   +11 more
doaj   +1 more source

Cerebral No‐Reflow after Thrombectomy: International Delphi Consensus on Definition and Imaging Assessment

Annals of Neurology, EarlyView.
Background The operational definition and imaging assessment of the no‐reflow phenomenon, a potential contributor to poor clinical outcome despite successful thrombectomy, remains debated. We aimed to develop expert‐based international consensus on the definition, assessment, and reporting standard of cerebral no‐reflow post‐thrombectomy. Methods Three‐
Adnan Mujanovic, Samantha Rivet, Adrien ter Schiphorst, Jean‐Claude Baron, Johannes Kaesmacher, Felix Ng, Cerebral No‐Reflow Delphi‐Consensus Group, Pooja Khatri, Xin Cheng, Andrea Zini, Maria Hernandez Perez, Ettore Nicolini, Marta Rubiera, Charlotte Rosso, Marie Luby, Victor Del Brutto, Christopher Favilla, Angel Chamorro, Angelika Hoffman, David Liebeskind, Sven P. R. Luijten, Moritz Hernandez Petzsche   +21 more
wiley   +1 more source

Spontaneous subarachnoid haemorrhage due to coarctation of aorta and intraspinal collaterals : a rare presentation [PDF]

, 2012
The occurrence of spontaneous subarachnoid haemorrhage (SAH) in association with coarctation of thoracic aorta and absence of intracranial aneurysm is a rare association.
Devara, Anil K.V., Uppu, S.C., Joseph, S.   +2 more
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