Results 71 to 80 of about 715,613 (310)

Neuroprotection in Subarachnoid Hemorrhage [PDF]

Stroke, 2010
Despite advances in aneurysm ablation and the initial management of patients presenting with aneurysmal subarachnoid hemorrhage, delayed cerebral ischemia remains a significant source of morbidity. Traditionally, delayed cerebral ischemia was thought to be a result of vasospasm of the proximal intracranial vessels, and clinical trials have relied ...
Daniel T, Laskowitz, Brad J, Kolls
openaire   +2 more sources

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source

Mitophagy alleviates neuronal damage after subarachnoid hemorrhage: Role of autophagy-targeting chimera 4

Neural Regeneration Research
This study investigated the role of autophagy-targeting chimera 4, a novel activator of autophagy that targets mitochondria, in a subarachnoid hemorrhage model.
Yongzhi Zhang, Jianqiao Li, Qi Sun, Peichun Zhou, Pei Wu, Zhiyong Ji, Yuchen Li, Huaizhang Shi   +7 more
doaj   +1 more source

Continuous Electroencephalography Predicts Delayed Cerebral Ischemia after Subarachnoid Hemorrhage: A Prospective Study of Diagnostic Accuracy

Annals of Neurology, 2018
Delayed cerebral ischemia (DCI) is a common, disabling complication of subarachnoid hemorrhage (SAH). Preventing DCI is a key focus of neurocritical care, but interventions carry risk and cannot be applied indiscriminately. Although retrospective studies
E. Rosenthal, S. Biswal, S. Zafar, K. O'Connor, Sophia C. Bechek, A. Shenoy, Emily J. Boyle, Mouhsin M. Shafi, E. Gilmore, Brandon Foreman, N. Gaspard, T. Leslie-Mazwi, J. Rosand, Daniel B. Hoch, C. Ayata, Sydney S. Cash, Andrew J. Cole, Aman B. Patel, M. Westover   +18 more
semanticscholar   +1 more source

Subarachnoid Haemorrhage in Malta : Are outcomes adversely affected due to lack of a local neurovascular service? [PDF]

, 2014
Objective: This study was performed to assess the incidence, treatment and outcome of non-traumatic Subarachnoid Haemorrhage (SAH) in an island which does not offer a neurovascular service and to determine whether such limitation is associated with a ...
Vella, Norbert, Dingli, Nicola, Galea Debono, Anthony, Aquilina, Josanne, Vella, Malcolm   +4 more
core  

A case of cerebral venous sinus thrombosis presented with SAH and isolated headache

Radiology Case Reports, 2023
Cerebral venous sinus thrombosis is a rare and challenging type of stroke. Coexistence of subarachnoid hemorrhage adds complexity to the diagnostic process leading to a missed or delayed diagnosis.
Nali Ahmed, MBChB, Mohamed Ibrahim, MBChB, FRCR, MD/PhD, Dmitriy Starostin, MBChB, FRCR   +2 more
doaj   +1 more source

Neutrophil Extracellular Traps Block Fibrinolysis in Ischemic Stroke

Annals of Neurology, EarlyView.
Objectives Intravenous thrombolysis (IVT) failure in acute ischemic stroke (AIS) is frequent, but its causes remain elusive. We investigated whether biologically relevant intrathrombus concentrations of tissue plasminogen activator (tPA) were achieved in failed IVT and whether neutrophil extracellular traps (NETs) contributed to this therapeutic ...
Mialitiana Solo Nomenjanahary, Jean‐Philippe Desilles, Fatima Zemali, Astride Perrot, Lucas Di Meglio, Sara Zalghout, Jéromine Fasille, Jérémy Neel, Stéphane Loyau, Julien Labreuche, Marie‐Charlotte Bourrienne, Dorothée Faille, François Delvoye, Véronique Ollivier, Sébastien Dupont, Jasmina Rogozarski, Nahida Brikci‐Nigassa, Robert L. Medcalf, Nadine Ajzenberg, Mikael Mazighi, Benoît Ho‐Tin‐Noé, the compoCLOT Study Group   +21 more
wiley   +1 more source

Non‐contrast CT Markers of Hematoma Expansion and Andexanet Response in Factor Xa Inhibitor‐Associated Intracerebral Hemorrhage: An Analysis from ANNEXa‐I Trial

Annals of Neurology, EarlyView.
In this post hoc analysis of the ANNEXa‐I trial (n = 434), we evaluated non‐contrast computed tomography (NCCT) markers of hematoma expansion (HE) in factor Xa inhibitor (FXai) –associated intracerebral hemorrhage (ICH). At least one NCCT marker was present in 72.1%, and HE (≥12.5 mL or ≥ 35% increase in hematoma volume) occurred in 31.8 ...
Koji Tanaka, Umberto Pensato, Mohamed Alshamrani, Aristeidis H. Katsanos, Pargol Balali, Sucharita Ray, Scott E. Kasner, Jan Beyer‐Westendorf, Danilo Toni, David J. Seiffge, Carlos Molina, David Tanne, Anna Członkowska, Arne G. Lindgren, Daniel Bereczki, Else C. Sandset, Georgios Tsivgoulis, Hanne Christensen, Jonathan M. Coutinho, Peter Verhamme, Pierre Amarenco, Robin Lemmens, Roland Veltkamp, Saskia Middeldorp, Thompson Robinson, Truman J. Milling, Wilfried Lang, Vitor Tedium‐Cruz, Mark Crowther, Lizhen Xu, Mikael Knutsson, Per Ladenvall, John W. Eikelboom, Mukul Sharma, Ashkan Shoamanesh, Andrew M. Demchuk   +35 more
wiley   +1 more source

Temporal muscle thickness and area with various characteristics data of the patients with aneurysmal subarachnoid hemorrhage who underwent endovascular coiling

Data in Brief, 2020
These data present the characteristics of patients with subarachnoid hemorrhage who underwent endovascular coiling. We retrospectively collected data from the medical records of Iwaki City Medical Center including physiological symptoms, laboratory data,
Masahito Katsuki, Yasuhiro Suzuki, Keiko Kunitoki, Yoshimichi Sato, Keisuke Sasaki, Shoji Mashiyama, Ryo Matsuoka, Elissa Allen, Hibiki Saimaru, Ryota Sugawara, Akinori Hotta, Teiji Tominaga   +11 more
doaj   +1 more source

Declining Admission and Mortality Rates for Subarachnoid Hemorrhage in Canada Between 2004 and 2015

Stroke, 2019
Background and Purpose— The purpose of this study was to assess recent trends in the admission and mortality rates for subarachnoid hemorrhage in Canada.
V. Chan, P. Lindsay, J. McQuiggan, B. Zagorski, M. Hill, C. O’Kelly   +5 more
semanticscholar   +1 more source