Results 91 to 100 of about 196,315 (301)

Treatment options for immune‐related adverse events associated with immune checkpoint inhibitors

British Journal of Pharmacology, EarlyView.
Abstract The immunotherapy revolution with the use of immune checkpoint inhibitors (ICIs) started with the clinical use of the first ICI, ipilimumab, in 2011. Since then, the field of ICI therapy has rapidly expanded — with the FDA approval of 10 different ICI drugs so far and their incorporation into the therapeutic regimens of a range of malignancies.
Yu Hua Chen, Tamás Kovács, Péter Ferdinandy, Zoltán V. Varga   +3 more
wiley   +1 more source

Serum thyroid hormone levels in preeclampsia women in Gorgan [PDF]

, 2014
Etiology of preeclampsia is clearly unknown. The aim of this study was to assess thyroid hormone levels in mild and severe preeclampsia women and compare them with healthy pregnant women.
Marjani, A., Rafeeinia, A., Teymoori, H.
core   +1 more source

Subclinical Hypothyroidism and Depression: A Systematic Review and Meta-Analysis

Frontiers in Endocrinology, 2019
Background: Thyroid function is closely associated with neuropsychological functions, including mental state and cognitive functions. Although thyroid function is routinely examined in persons with depressive symptom, the association between subclinical ...
Rong Tang, Jian Wang, Lili Yang, Xiaohong Ding, Yufan Zhong, Jiexue Pan, Haiyan Yang, L. Mu, Xia Chen, Zimiao Chen   +9 more
semanticscholar   +1 more source

Subclinical hypothyroidism and cardiovascular risk

Clinical Hemorheology and Microcirculation, 2014
BACKGROUND: Subclinical hypothyroidism (SCH) has been suggested to be associated with increased cardiovascular risk by different mechanisms. Several cardiovascular risk factors have been analysed, but yielded controversial results. OBJECTIVES: We aimed to analyse whether there are differences in several cardiovascular risk markers, such as
Amparo Vayá, Olaya Rubio, Antonio Hernández-Mijares, Cristina Giménez, Ana Sarnago, Amparo Alba, Rosa Cámara   +6 more
openaire   +5 more sources

Testicular Function After Immune‐Checkpoint Inhibitors Treatment

Clinical Endocrinology, EarlyView.
ABSTRACT Objective To investigate the effects of immune‐checkpoint inhibitors (ICIs) on spermatogenesis and testicular endocrine function in reproductive‐age men with melanoma. Design Prospective, mixed longitudinal and cross‐sectional cohort study. Patients Twenty‐nine men aged 19–46 years undergoing ICI therapy for melanoma at two Australian centres ...
Andrea Boutros, Amanda Idan, Sue Sleiman, Feyrous Bacha, Ting Zhang, Veena Jayadev, Alexander M. Menzies, Georgina V. Long, David J. Handelsman   +8 more
wiley   +1 more source

Monitoring thyroid function status in elderly patients on amiodarone [PDF]

, 2006
Objectives: To evaluate whether elderly patients on amiodarone were having their thyroid function status monitored as recommended in the literature and to identify the frequency and type of thyroid function test abnormalities noted.
Fiorini, Anthony
core  

Subclinical Hypothyroidism in Children: When a Replacement Hormonal Treatment Might Be Advisable

Frontiers in Endocrinology, 2019
Aim of this mini review was to analyze the main variables which should be taken into account when the decision regarding a possible treatment with L-T4 has to be considered for a child with subclinical hypothyroidism (SH).
G. Crisafulli, T. Aversa, G. Zirilli, G. Pajno, D. Corica, F. De Luca, M. Wasniewska   +6 more
semanticscholar   +1 more source

The Prevalence of Thyroid Disorders in Patients With Vitiligo: A Systematic Review and Meta-Analysis

Frontiers in Endocrinology, 2019
Background: Associations between vitiligo and thyroid disorders have been suggested, However, the prevalence of thyroid disorders in vitiligo vary widely.Purpose: To conduct a systematic review and meta-analysis assessing the prevalence of thyroid ...
Jinping Yuan, Chong Sun, Shibin Jiang, Yansong Lu, Yuhui Zhang, Xing-Hua Gao, Yan Wu, Hong-Duo Chen   +7 more
doaj   +1 more source

Dual Role of Natural Killer Cells in Early Pregnancy: Immunopathological Implications and Therapeutic Potential in Recurrent Spontaneous Abortion and Recurrent Implantation Failure

Cell Proliferation, EarlyView.
This article elaborates on the role of NK cells in early pregnancy from multiple perspectives, including molecular mechanisms and therapeutic interventions. It also discusses how NK cell dysfunction contributes to RSA and RIF, aiming to provide insights for future research on NK cell mechanisms and clinical treatment of RSA and RIF.
Defeng Guan, Zhou Chen, Yuhua Zhang, Wenjie Sun, Lifei Li, Xia Huang   +5 more
wiley   +1 more source

Are fluoride levels in drinking water associated with hypothyroidism prevalence in England? A large observational study of GP practice data and fluoride levels in drinking water [PDF]

, 2015
Background While previous research has suggested that there is an association between fluoride ingestion and the incidence of hypothyroidism, few population level studies have been undertaken.
Bath, Chana, Cooper, D Lowery, Day, European Commission, Feltman, Flynn, Galletti, Gillam, Harrison, Jooste, Klein, Larsen, Lee, National Research Council (NRC), Peckham, S Peckham, S Spencer, Vanderpump, Vanderpump, Warren, Wilson   +22 more
core   +1 more source