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Abstract Subclinical hypothyroidism is defined biochemically as the association of a raised serum thyroid-stimulating hormone (TSH) concentration with normal circulating concentrations of free thyroxine (T4) and free triiodothyronine (T3). The term subclinical hypothyroidism implies that patients should be asymptomatic, although symptoms
Ernst Nyström +4 more
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Overt and Subclinical Hypothyroidism
Hypothyroidism denotes deficient production of thyroid hormone by the thyroid gland and can be primary (abnormality in thyroid gland itself) or secondary/central (as a result of hypothalamic or pituitary disease). The term ‘subclinical hypothyroidism’ is
Deepak Khandelwal, Nikhil Tandon
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Subclinical Hypothyroidism: A Review of Neuropsychiatric Aspects
The authors review current information about the prevalence, causes, course, and consequences of subclinical hypothyroidism. There is evidence that subclinical hypothyroidism may be associated with cognitive dysfunction, mood disturbance, and diminished ...
Cort Pedersen, Robert N Golden
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Subclinical hypothyroidism in pregnancy
Current Opinion in Endocrinology, Diabetes & Obesity, 2019Purpose of review Subclinical hypothyroidism (SCH) is a common diagnosis among women of reproductive age. The importance of sufficient maternal thyroid supply during pregnancy is well known. Nevertheless, the effects of SCH during pregnancy and the efficacy of its treatment on maternofetal outcomes are not well established ...
Freddy J K, Toloza +2 more
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Subclinical hypothyroidism in the elderly
Archives of Gerontology and Geriatrics, 1996Grade 2,3 and 4 hypothyroidism in the elderly, globally defined as subclinical hypothyroidism, is the object of this minireview. Attention is focused on the prevalence, on the causes and particularly on the clinical features that, in spite of the definition, frequently occur: these are summarized in cognitive impairment, mood disorders, lipid ...
G, Valenti, A, Fabbo
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Subclinical hypothyroidism in childhood
Archives of Disease in Childhood, 2010Subclinical hypothyroidism (SH) is defined as an elevated thyroid stimulating hormone (TSH) in association with a normal total or free thyroxine (T4) or triiodothyronine (T3). It is frequently encountered in both neonatology and general paediatric practice; however, its clinical significance is widely debated.
M J, O'Grady, D, Cody
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Subclinical hypothyroidism and subclinical hyperthyroidism
Expert Review of Endocrinology & Metabolism, 2010Subclinical thyroid dysfunction occurs when peripheral thyroid hormone levels are within the normal laboratory reference range and the serum thyroid-stimulating hormone (TSH or thyrotropin) level is greater than normal (subclinical hypothyroidism) or less than normal (subclinical hyperthyroidism; TSH normal laboratory reference range: 0.3-5.0 mIU/l ...
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An update on subclinical hypothyroidism and subclinical hyperthyroidism
Expert Review of Endocrinology & Metabolism, 2014Subclinical thyroid dysfunction is characterized by normal levels of peripheral thyroid hormone, paired with a TSH level that is either lower than (subclinical hyperthyroidism) or higher than (subclinical hypothyroidism) the normal laboratory reference range. Slight shifts in peripheral hormone levels result in significant serum TSH changes.
Mitra M, Fatourechi, Vahab, Fatourechi
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Hypothyroidism and Subclinical Hypothyroidism in the Older Patient
The Consultant Pharmacist, 2011To review the etiology, precipitating factors, clinical findings, screening recommendations, and treatment for primary hypothyroidism and subclinical hypothyroidism in the older patient.A PubMed search of English language articles using a combination of words: elderly, thyroid, hypothyroid,* subclinical hypothyroid,* etiology, screening, diagnosis, and
Samuel L, Gurevitz +3 more
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Homocysteine Concentrations in Subclinical Hypothyroidism
Endocrine Research, 2004Hyperhomocysteinemia is considered to be an independent risk factor for atherosclerotic heart disease, including coronary artery disease (CAD). It is already known that overt hypothyroidism gives rise to a slight hyperhomocysteinemia. However, the effects of subclinical hypothyroidism on the levels of homocysteine are not known.
Sengul, E +4 more
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