Results 51 to 60 of about 5,940 (179)

Healthy Aging Men Do Not Suffer From Relevant Limitations of Their Reproductive Functions

Andrology, EarlyView.
Abstract Background While metabolic disorders are well‐established contributors to testosterone decline and erectile dysfunction (ED), little is known about the natural progression of reproductive parameters in healthy aging men. Objectives This study aimed to evaluate longitudinal changes in reproductive parameters and sought to determine the ...
Simone Bier, Jann‐Frederik Cremers, Phillip Schrage, Amelie Körtje, Claudia Krallmann, Sabine Kliesch, Jörg Gromoll, Sandra Laurentino, Michael Zitzmann   +8 more
wiley   +1 more source

Treatment options for immune‐related adverse events associated with immune checkpoint inhibitors

British Journal of Pharmacology, EarlyView.
Abstract The immunotherapy revolution with the use of immune checkpoint inhibitors (ICIs) started with the clinical use of the first ICI, ipilimumab, in 2011. Since then, the field of ICI therapy has rapidly expanded — with the FDA approval of 10 different ICI drugs so far and their incorporation into the therapeutic regimens of a range of malignancies.
Yu Hua Chen, Tamás Kovács, Péter Ferdinandy, Zoltán V. Varga   +3 more
wiley   +1 more source

Endothelial dysfunction and the risk of atherosclerosis in overt and subclinical hypothyroidism

Endocrine Connections, 2018
Hypothyroidism is associated with increased risk of atherosclerosis. We assessed carotid intima-media thickness (CIMT), as a marker of atherosclerosis, and endothelial function in patients with hypothyroidism.
Aasem Saif, Shrook Mousa, Maha Assem, Nashwa Tharwat, Alaa Abdelhamid   +4 more
doaj   +1 more source

Evaluating the Link Between Thyroid Function Test Results and Levothyroxine Dose in the Management of Hypothyroidism: Can We Improve Dosing Regimes?

Clinical Endocrinology, EarlyView.
ABSTRACT Introduction Over 10 million thyroid function tests (TFTs) are carried out in England each year, most requests coming from primary care. Our previous work showed that only 25% of results for patients being treated with Levothyroxine fell within the TSH/FT4 boundary circumscribing 75% of untreated individuals.
Adrian H. Heald, Lakdasa D. Premawardhana, Peter N. Taylor, Suhani Bahl, Onyebuchi E. Okosieme, Anthony A. Fryer, Antonio Bianco, Colin M. Dayan, Michael P. Stedman   +8 more
wiley   +1 more source

Pathogenesis and Therapeutics for Chronic Pruritus of Unknown Origin: A Systematic Review

International Journal of Dermatology, EarlyView.
ABSTRACT Chronic pruritus of unknown origin (CPUO) is a distressing condition characterized by persistent itch lasting over 6 weeks without an identifiable cause. The underlying mechanisms remain poorly understood, complicating diagnosis and treatment.
Yagiz Matthew Akiska, Isha Gandhi, Robert Adler, Deena Fayyad, Perya Bhagchandani, Shabnam Afzal, Waleed Adawi, Shivani Patel, Shawn G. Kwatra   +8 more
wiley   +1 more source

The Prevalence of Thyroid Disorders in Patients With Vitiligo: A Systematic Review and Meta-Analysis

Frontiers in Endocrinology, 2019
Background: Associations between vitiligo and thyroid disorders have been suggested, However, the prevalence of thyroid disorders in vitiligo vary widely.Purpose: To conduct a systematic review and meta-analysis assessing the prevalence of thyroid ...
Jinping Yuan, Chong Sun, Shibin Jiang, Yansong Lu, Yuhui Zhang, Xing-Hua Gao, Yan Wu, Hong-Duo Chen   +7 more
doaj   +1 more source

Systemic Disease Associations of Oral Lichenoid Disease: A Retrospective Case–Control Study

Oral Diseases, EarlyView.
ABSTRACT Objective To analyze the association between oral lichen planus (OLP), oral lichenoid lesions (OLL), and other comorbidities. Material and Methods A case–control study of 205 OLP, 96 OLL patients, and 301 age‐ and sex‐matched controls from Kuopio University Hospital was performed.
Mari Vehviläinen, Tuomas Selander, Tuula Salo, Maria Siponen   +3 more
wiley   +1 more source

Pharmacologic Treatment of Kleine–Levin Syndrome: A Case Report and Comprehensive Review of Therapeutic Options

Neuropsychopharmacology Reports, Volume 46, Issue 1, March 2026.
A 12‐year‐old girl with Klein‐Levin syndrome showed central hypopneas and REM sleep without atonia on 24‐h polysomnography, which normalized after clarithromycin treatment alongside clinical remission. ABSTRACT Kleine–Levin syndrome (KLS) is a rare disorder with limited literature on treatment options and efficacy, especially in adolescents.
Sarisa Thawongit, Vorasith Siripornpanich, Lunliya Thampratankul   +2 more
wiley   +1 more source

The Influence of Health Literacy on the Control of Hypothyroidism in Patients Under Levothyroxine Treatment

Clinical Endocrinology, Volume 104, Issue 2, Page 167-174, February 2026.
ABSTRACT Objective To investigate the association between health literacy levels and biochemical control of hypothyroidism, measured by serum TSH and free thyroxine (FT4) levels, in patients receiving levothyroxine (L‐T4) therapy. Methods We conducted a cross‐sectional study at the Thyroid Disorders Outpatient Clinic, Escola Paulista de Medicina ...
Jessyka Krause Meneses, Daniella Araujo Muniz, Débora Moroto, João Roberto Maciel Martins, Carolina Castro Porto Silva Janovsky   +4 more
wiley   +1 more source

Possible association between subclinical hypothyroidism and age at menopause in Colombian women

Gynecological Endocrinology
Objective To evaluate the association between subclinical hypothyroidism with early menopause, premature menopause, and last menstrual bleeding before the natural age of menopause.Methods This was a cross-sectional study conducted in 643 postmenopausal ...
Álvaro Monterrosa-Castro, Angelica Monterrosa-Blanco, Sandra Sánchez-Zarza   +2 more
doaj   +1 more source