Results 51 to 60 of about 39,625 (280)

Long‐Term Outcomes of Reduced Intensity Conditioning Hematopoietic Stem Cell Transplantation for Systemic Sclerosis Patients with Impaired Cardiac Function

Arthritis &Rheumatology, Accepted Article.
Objective High intensity conditioning autologous hematopoietic stem cell transplantation (AHSCT) is standard of care for patients with advanced SSc. The role of reduced intensity conditioning (RIC) prior to AHSCT in this population remains unclear. We conducted this study to determine the long‐term outcomes of RIC AHSCT in SSc patients with cardiac ...
Yonatan Lean, Carrie Richardson, Anthony Esposito, Katy Bedjeti, George E. Georges   +4 more
wiley   +1 more source

To Treat or Not to Treat Subclinical Hypothyroidism, What Is the Evidence?

Medicina, 2020
Objective: levothyroxine prescriptions have increased remarkably during the last decade, and it is most likely to be prescribed in subclinical hypothyroidism. The aim of this review was to present data on when levothyroxine treatment should be initiated,
Jan Calissendorff, Henrik Falhammar
doaj   +1 more source

Evaluation of Serum Prolactin Level in Patients of Subclinical and Overt Hypothyroidism [PDF]

Journal of Clinical and Diagnostic Research, 2015
Background: Prolactin secretion is controlled by prolactin inhibitor factor that is secreted from hypothalamus; factors like vasoactive inhibitory peptide (VIP) and thyroid releasing hormone (TRH) lead to increase in prolactin secretion ...
Parul Goel, Kahkasha, Shveta Narang, Bharat K Gupta, Kapil Goel   +4 more
doaj   +1 more source

Risk of cardiac, neuropsychiatric and musculoskeletal adverse events with levothyroxine: Systematic review

British Journal of Clinical Pharmacology, EarlyView.
Abstract Levothyroxine (LT4) is the standard treatment for hypothyroidism and the most widely prescribed medication worldwide. Although generally safe, regulatory reports list potential cardiac, neuropsychiatric and musculoskeletal adverse events (AEs). Clarifying their clinical relevance is essential.
Bala Swetha Baskaran, Mohammad Ali Omrani, Flory T. Muanda   +2 more
wiley   +1 more source

Thyroxine treatment with softgel capsule formulation. Usefulness in hypothyroid patients without malabsorption [PDF]

, 2018
Background: Levothyroxine sodium (LT4) is the therapy of choice for hypothyroidism. In the last decade, new LT4 formulations, such as liquid and softgel capsules, became available. Even if some evidence has been reached in the efficacy of liquid LT4 in
Centanni, Marco, Giovanella, Luca, Trimboli, Pierpaolo, Virili, Camilla   +3 more
core   +2 more sources

Ashwagandha: Is It Safe? Part 2: A Preclinical Evidence Review

Phytotherapy Research, EarlyView.
ABSTRACT The preclinical evidence for the safety of ashwagandha (Withania somnifera (L.) Dunal, AS) is reviewed, and its preparations (extracts) and constituents, from the general toxicity in animal models to in vitro and cell culture studies, which may elucidate mechanisms of action and explain clinical case reports.
Elizabeth M. Williamson, Thomas Brendler
wiley   +1 more source

Study protocol; thyroid hormone replacement for untreated older adults with subclinical hypothyroidism - a randomised placebo controlled trial (TRUST) [PDF]

, 2017
Background: Subclinical hypothyroidism (SCH) is a common condition in elderly people, defined as elevated serum thyroid-stimulating hormone (TSH) with normal circulating free thyroxine (fT4).
Bauer, Douglas, Blum, Manuel, Browne, John, Byrne, Stephen, Collet, Tinh-Hai, Dekkers, Olaf M., Den Elzen, Wendy P.J., Du Puy, Robert, Ford, Ian, Gussekloo, Jacobijn, Hendry, Kirsty, Hurley, Caroline, Jukema, J. Wouter, Kean, Sharon, Kearney, Patricia M., McCarthy, Vera, Mooijaart, Simon, Poortvliet, Rosalinde K.E., Quinn, Terence J., Rodondi, Nicolas, Sattar, Naveed, Smit, Jan W.A., Stott, David J., Watt, Torquil, Westendorp, Rudi G.J.   +24 more
core   +12 more sources

Review of the risks and/or benefits of thyroxine treatment in ‘mild’ subclinical hypothyroidism [PDF]

, 2013
Subclinical hypothyroidism (SCH) is a form of mild thyroid failure and is a commonly encountered condition in clinical practice. It denotes the presence of a raised serum thyroid stimulating hormone (TSH) and normal serum free thyroid hormone ...
Agius, Rachel
core  

Evaluation of Potential Hormonal Activities of Ashwagandha (Withania somnifera)

Phytotherapy Research, EarlyView.
ABSTRACT Ashwagandha is a widely used herb in traditional medicine systems, particularly Ayurveda. Despite its extensive tradition, growing concerns regarding its potential endocrinological effects have prompted scientific scrutiny. This review systematically evaluates the current preclinical, clinical, and case study evidence concerning AS's effects ...
Günter Vollmer, Thomas Brendler
wiley   +1 more source

[Subclinical hypothyroidism].

Wiadomosci lekarskie (Warsaw, Poland : 1960), 2008
Subclinical hypothyroidism, defined by elevated serum levels of thyroid stimulating hormone (TSH) with normal levels of free thyroid hormones, belongs to the most common disorders encountered in an endocrine office practice. It is assumed that elevated TSH levels in patients with subclinical hypothyroidism do not reflect pituitary compensation to ...
Robert, Krysiak, Bogdan, Marek, Bogusław, Okopień   +2 more
  +6 more sources