Results 71 to 80 of about 39,625 (280)

Spontaneous Bacterial Peritonitis in Subclinical Hypothyroidism [PDF]

, 2013
Hypothyroidism is an uncommon cause of ascites. Here we describe a case of a 75 year-old female patient with spontaneous bacterial peritonitis and subclinical hypothyroidism that resolved with thyroid replacement and antibiotic therapy respectively ...
Dalip Gupta, Gaurav Kapur, Munish, Preyander Thakur, Sachin Sondhi, Vivek Chabra   +5 more
core   +1 more source

Treatment options for immune‐related adverse events associated with immune checkpoint inhibitors

British Journal of Pharmacology, EarlyView.
Abstract The immunotherapy revolution with the use of immune checkpoint inhibitors (ICIs) started with the clinical use of the first ICI, ipilimumab, in 2011. Since then, the field of ICI therapy has rapidly expanded — with the FDA approval of 10 different ICI drugs so far and their incorporation into the therapeutic regimens of a range of malignancies.
Yu Hua Chen, Tamás Kovács, Péter Ferdinandy, Zoltán V. Varga   +3 more
wiley   +1 more source

The Prevalence of Thyroid Disorders in Patients With Vitiligo: A Systematic Review and Meta-Analysis

Frontiers in Endocrinology, 2019
Background: Associations between vitiligo and thyroid disorders have been suggested, However, the prevalence of thyroid disorders in vitiligo vary widely.Purpose: To conduct a systematic review and meta-analysis assessing the prevalence of thyroid ...
Jinping Yuan, Chong Sun, Shibin Jiang, Yansong Lu, Yuhui Zhang, Xing-Hua Gao, Yan Wu, Hong-Duo Chen   +7 more
doaj   +1 more source

Thyroid hormone levels within reference range are associated with heart rate, cardiac structure, and function in middle-aged men and women [PDF]

, 2013
Background: Triiodothyronine (T3) has many effects on the heart, and marked changes in cardiac function and structure occur in patients with (subclinical) thyroid disease. We investigated whether between-subject variation in thyroid hormone levels within
De Buyzere, Marc, Gillebert, Thierry, Kaufman, Jean, Rietzschel, Ernst, ROEF, GREET, Taes, Youri, Van daele, Caroline   +6 more
core   +1 more source

Evaluating the Link Between Thyroid Function Test Results and Levothyroxine Dose in the Management of Hypothyroidism: Can We Improve Dosing Regimes?

Clinical Endocrinology, EarlyView.
ABSTRACT Introduction Over 10 million thyroid function tests (TFTs) are carried out in England each year, most requests coming from primary care. Our previous work showed that only 25% of results for patients being treated with Levothyroxine fell within the TSH/FT4 boundary circumscribing 75% of untreated individuals.
Adrian H. Heald, Lakdasa D. Premawardhana, Peter N. Taylor, Suhani Bahl, Onyebuchi E. Okosieme, Anthony A. Fryer, Antonio Bianco, Colin M. Dayan, Michael P. Stedman   +8 more
wiley   +1 more source

Pathogenesis and Therapeutics for Chronic Pruritus of Unknown Origin: A Systematic Review

International Journal of Dermatology, EarlyView.
ABSTRACT Chronic pruritus of unknown origin (CPUO) is a distressing condition characterized by persistent itch lasting over 6 weeks without an identifiable cause. The underlying mechanisms remain poorly understood, complicating diagnosis and treatment.
Yagiz Matthew Akiska, Isha Gandhi, Robert Adler, Deena Fayyad, Perya Bhagchandani, Shabnam Afzal, Waleed Adawi, Shivani Patel, Shawn G. Kwatra   +8 more
wiley   +1 more source

Subclinical Hypothyroidism and the Risk of Stroke Events and Fatal Stroke: An Individual Participant Data Analysis. [PDF]

, 2015
OBJECTIVE: The objective was to determine the risk of stroke associated with subclinical hypothyroidism. DATA SOURCES AND STUDY SELECTION: Published prospective cohort studies were identified through a systematic search through November 2013 without ...
Bakker, S.J.L., Bauer, D.C., Baumgartner, C., Blum, M.R., Bremner, A., Cappola, A.R., Ceresini, G., Chaker, L., Collet, T.H., Dehghan, A., Drechsler, C., Dullaart, R.P., Elzen, W.P.J. den, Ferrucci, L., Ford, I., Franco, O.H., Franklyn, J.A., Gussekloo, J., Hofman, A., Iervasi, G., Ikram, M.A., Imaizumi, M., Jukema, J.W., Khaw, K.T., Luben, R.N., Maciel, R.M.B., Medici, M., Newman, A.B., Peeters, R.P., Portegies, M.L.P., Razvi, S., Rodondi, N., Sgarbi, J.A., Stott, D.J., Thyroid Studies Collaboration, Volzke, H., Walsh, J.P., Wanner, C., Westendorp, R.G.   +38 more
core   +1 more source

The causal effects of hypothyroidism on cardiovascular disease: Bidirectional and multivariable Mendelian randomization study

Journal of Diabetes Investigation, EarlyView.
Our study suggests bidirectional causal associations between hypothyroidism and both coronary artery disease (CAD) and myocardial infarction (MI). Moreover, hypothyroidism contributes to an increased risk of peripheral atherosclerosis (PAS). ABSTRACT Background Whether hypothyroidism and cardiovascular disease (CVD) are causally related remains ...
Xuan Bai, Mengyi Sun, Xu Han
wiley   +1 more source

Possible association between subclinical hypothyroidism and age at menopause in Colombian women

Gynecological Endocrinology
Objective To evaluate the association between subclinical hypothyroidism with early menopause, premature menopause, and last menstrual bleeding before the natural age of menopause.Methods This was a cross-sectional study conducted in 643 postmenopausal ...
Álvaro Monterrosa-Castro, Angelica Monterrosa-Blanco, Sandra Sánchez-Zarza   +2 more
doaj   +1 more source

Evaluation of the Female Patients with Subclinical Hypothyroidism by Brainstem Auditory Evoked Potentials: Case-Control Study [PDF]

Journal of Clinical and Diagnostic Research, 2017
Introduction: Hypothyroidism, a common endocrinological disorder is quite prevalent in its subclinical state in the adult population. Nervous system involvement is frequent in hypothyroidism with documentation of peripheral and central conduction ...
Sangeeta Gupta, Rajesh Kaiti, Gaurav Gupta   +2 more
doaj   +1 more source