Results 201 to 210 of about 3,404,423 (317)

Treatment options for immune‐related adverse events associated with immune checkpoint inhibitors

British Journal of Pharmacology, EarlyView.
Abstract The immunotherapy revolution with the use of immune checkpoint inhibitors (ICIs) started with the clinical use of the first ICI, ipilimumab, in 2011. Since then, the field of ICI therapy has rapidly expanded — with the FDA approval of 10 different ICI drugs so far and their incorporation into the therapeutic regimens of a range of malignancies.
Yu Hua Chen, Tamás Kovács, Péter Ferdinandy, Zoltán V. Varga   +3 more
wiley   +1 more source

A UK key opinion leader perspective: Navigating the immunological and logistical transformation brought by stem cell‐derived islets for the treatment of type 1 diabetes

Diabetic Medicine, EarlyView.
Abstract Aims To explore UK key‐opinion leader perspectives on the future role of stem cell‐derived islets (sc‐islets) in islet transplantation for people with type 1 diabetes (T1D). Methods Four UK‐based key‐opinion leaders evaluated current limitations of donor islet transplantation and reviewed emerging evidence, clinical pathways and logistical ...
Thomas Strakosch, Shareen Forbes
wiley   +1 more source

Elevated levels of monocyte activation markers are associated with subclinical atherosclerosis in men with and those without HIV infection.

Journal of Infectious Diseases, 2015
Rebeccah A. McKibben, J. Margolick, S. Grinspoon, Xiuhong Li, F. Palella, L. Kingsley, M. Witt, R. George, L. Jacobson, M. Budoff, R. Tracy, T. Brown, W. Post   +12 more
semanticscholar   +1 more source

Factors Affecting Immune Reconstitution Post‐Allogeneic HSCT in Children: The Case for an Individualized Approach to Vaccination

European Journal of Haematology, EarlyView.
ABSTRACT Allogeneic hematopoietic stem cell transplantation (HSCT) is increasingly used to treat malignant and non‐malignant diseases. Following allogeneic HSCT, patients are particularly vulnerable to vaccine‐preventable diseases (VPD) because conditioning depletes immune cells, including memory cells.
Hélène Buvelot, Frederic Baleydier, Laure Pittet, Geraldine Blanchard‐Rohner   +3 more
wiley   +1 more source

Whole Blood Transcriptomic Analysis of Sickle Cell Trait

European Journal of Haematology, EarlyView.
ABSTRACT Sickle cell trait (SCT) is the heterozygous carrier state for the HBB missense variant which causes sickle cell disease (SCD). SCT has been associated with increased risk of venous thromboembolism and chronic kidney disease as well as alterations in clinical laboratory parameters. To investigate differential gene expression in SCT, we used RNA
Mari Johnson, Yanwei Cai, Ana Gabriela Vasconcelos, Peter Orchard, Paul L. Auer, Guillaume Lettre, Jia Wen, Nora Franceschini, Charles Kooperberg, Wei Sun, Li Hsu, Laura M. Raffield, Alex P. Reiner   +12 more
wiley   +1 more source

Dynamics and Differences in Systemic and Local Immune Responses After Vaccination With Inactivated and Live Commercial Vaccines and Subsequent Subclinical Infection With PRRS Virus. [PDF]

Front Immunol, 2019
Toman M, Celer V, Kavanová L, Levá L, Frolichova J, Ondráčková P, Kudláčková H, Nechvátalová K, Salat J, Faldyna M.   +9 more
europepmc   +1 more source

Candidate serum metabolite biomarkers of subclinical Haemonchus contortus infection in sheep [PDF]

Hamza Jawad, Désirée Gellatly, Yaogeng Lei, Sean Thompson, Shima Borzouei, Olufemi Osonowo, John S. Gilleard, Younes Miar, Seyed Ali Goldansaz, Ghader Manafiazar   +9 more
openalex   +1 more source

The interacting etiologies of hippocampal sclerosis in epilepsy: A scoping review

Epilepsia, EarlyView.
Abstract According to the International League Against Epilepsy classification, mesial temporal lobe epilepsy with hippocampal sclerosis (MTLE‐HS) is considered an epilepsy syndrome. Several etiologies may precede HS, but there is little overview in the literature about these etiologies.
Boris Deleu, Jules Jeuris, Wim Van Paesschen   +2 more
wiley   +1 more source

Brucella abortus in the bitch: subclinical infection associated with urinary excretion [PDF]

, 1979
S. R. Bicknell, R. A. Bell
openalex   +1 more source

HIV Infection Is Associated With Progression of Subclinical Carotid Atherosclerosis.

Clinical Infectious Diseases, 2015
D. Hanna, W. Post, J. Deal, H. Hodis, L. Jacobson, W. Mack, K. Anastos, S. Gange, A. Landay, J. Lazar, F. Palella, P. Tien, M. Witt, X. Xue, M. Young, R. Kaplan, L. Kingsley   +16 more
semanticscholar   +1 more source