Results 231 to 240 of about 139,450 (287)

Treatment options for immune‐related adverse events associated with immune checkpoint inhibitors

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract The immunotherapy revolution with the use of immune checkpoint inhibitors (ICIs) started with the clinical use of the first ICI, ipilimumab, in 2011. Since then, the field of ICI therapy has rapidly expanded — with the FDA approval of 10 different ICI drugs so far and their incorporation into the therapeutic regimens of a range of malignancies.
Yu Hua Chen   +3 more
wiley   +1 more source

UK Biobank: Transforming drug discovery and precision medicine

open access: yesBritish Journal of Pharmacology, EarlyView.
UK Biobank is a large‐scale, prospective study with extensive genetic and phenotypic data on half a million individuals. Volunteers, aged between 40 and 69 years, were recruited between 2006 and 2010 from the general population of the United Kingdom.
Jelena Bešević   +11 more
wiley   +1 more source

Ten‐Year Results of a Prospective Study on One‐Piece Zirconia Oral Implants for Single‐Tooth Reconstruction

open access: yesClinical Oral Implants Research, EarlyView.
ABSTRACT Objectives The intention of this 10‐year prospective cohort investigation was to clinically and radiographically investigate the outcomes of a one‐piece zirconia implant system for single‐tooth replacement. Materials and Methods A total of 65 patients received 66 single‐tooth implants restored with all‐ceramic crowns.
Ralf‐Joachim Kohal   +6 more
wiley   +1 more source

Prevalence and Associated Factors of Olfactory and Gustatory Loss in Patients With Nasal Septal Deviation

open access: yesClinical Otolaryngology, EarlyView.
ABSTRACT Objectives This study aimed to evaluate the olfactory and gustatory functions of patients with nasal septal deviation (NSD) and identify the factors associated with olfactory loss (OL) and gustatory loss (GL). Design and Setting Retrospective data analysis of cohort group. Participants Two‐hundred fourteen adult patients with NSD at a tertiary
Ja‐Yoon Kim   +3 more
wiley   +1 more source

Measuring and Managing Obesity in Pregnancy Using the Edmonton Obesity Staging System: A Scoping Review

open access: yesClinical Obesity, EarlyView.
ABSTRACT Emerging evidence and clinical practice guidelines have highlighted that obesity, defined as a chronic disease characterised by excess or dysfunctional adipose tissue, may not be accurately measured or understood by solely relying on body mass index (BMI) which is a measure of size not functionality.
Taniya S. Nagpal   +3 more
wiley   +1 more source

S1 guideline for imaging diagnostics for skin diseases

open access: yesJDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Non‐invasive imaging techniques allow a quick and easy in vivo examination of the skin with different penetration depths and resolution depending on the applied technology. Established methods such as dermoscopy and high‐resolution sonography of the skin have been an integral part of everyday life for decades.
Maximilian Deußing   +21 more
wiley   +1 more source

Assessing the independent and combined impact of obesity and gestational diabetes mellitus on adverse maternal outcomes: A systematic review and meta‐analysis

open access: yesDiabetic Medicine, EarlyView.
Abstract Aims To evaluate the impact of obesity, with or without gestational diabetes mellitus (GDM), on adverse maternal outcomes and determine whether the combination of obesity and GDM confers a greater risk compared to obesity alone. Methods We systematically searched MEDLINE, EMBASE, Scopus, CINAHL and the WoS Core Collection, identifying 19 ...
Tessa L. Weir   +2 more
wiley   +1 more source

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