Results 171 to 180 of about 142,490 (305)

From Energy Deprivation Stress to Catalytic Adaptation of Reductive Dehalogenase TmrA for 1,1-DCA Dechlorination: An Experimental and in Silico Study. [PDF]

Microb Biotechnol
Ren Y, Landers E, Lee M, Manefield M.
europepmc   +1 more source

Targeting hexokinase 2 to induce breast cancer cell senescence

British Journal of Pharmacology, EarlyView.
Background and Purpose Hexokinase 2 (HK2) is a key enzyme linked to high tumour cell proliferation. Its inhibitors such as 3‐bromopyruvic acid (3‐BP) induce cancer cell death, highlighting HK2 modulation as potential anti‐cancer treatment. However, standard chemotherapies often cause the emergence of senescent cancer cells, which goes along with cell ...
Helmut Bischof, Katarina Cisarova, Sandra Burgstaller, Mia Schwerer, Markus Absenger‐Novak, Philipp J. Jost, Roland Malli, Wolfgang F. Graier, Robert Lukowski   +8 more
wiley   +1 more source

First human cell-based cultivation system for the syphilis spirochete Treponema pallidum. [PDF]

BMC Microbiol
Bosák J, Hrala M, Pospíšilová P, Bosakova M, Šmajs D.   +4 more
europepmc   +1 more source

Autophagy Inhibition by Fangji Huangqi Decoction Enhances Tumor Immunogenicity and Potentiates PD‐1 Blockade

Cancer Science, EarlyView.
In tumor cells, MHC‐I is typically degraded through autophagy, leading to reduced antigen presentation. However, Fangji Huangqi Decoction (FJHQ), acting as an autophagy inhibitor, suppresses lysosomal acidification, which in turn inhibits the degradation of MHC‐I. This results in increased surface expression of MHC‐I on tumor cells.
Yuxiao Jiang, Shiji Zeng, Dingye Wang, Junbo Jiang, Zhenzhen Li, Jingbi Li, Dan Chen, Xu Zhao, Zheng Ying, Yuehua Deng, Qianwei Cai, Silin Mai, Jiayi Zheng, Qiaohong Yang, Fang Liu, Biaoyan Du, Jianyong Xiao, Xiaoyi Liu, Kun Wang   +18 more
wiley   +1 more source

Book Review of \u3cem\u3eMuslim Fashion: Contemporary Style Cultures\u3c/em\u3e, by Reina Lewis [PDF]

, 2017
Othman, Enaya
core   +1 more source

The Brief Case: Adjudication of discrepant genotypic and phenotypic antimicrobial susceptibility testing results in a patient with <i>Staphylococcus aureus</i> bacteremia. [PDF]

J Clin Microbiol
Reyes Curcio F, McCallum J, Borrelli G, Orr B, Weiss Z, Nussbaum EZ.   +5 more
europepmc   +1 more source

A Walk in the Park: Influence of Natural Co‐Exposure to Grass Pollen and Fungal Spores on Nasal Mycobiome and Cytokine Responses

Clinical &Experimental Allergy, EarlyView.
Volunteers stayed 3 h indoors and followed 1 h outdoors in a flowering meadow. Nasal mycobiome was analysed and aeroallergen content measured in nasal filters. Airborne fungal spores were quantified and fungal isolates were sequenced. Isolated fungal spores were used for stimulation of nasal epithelial cells.
Annika Eggestein, Denise Rauer, Selina M. Herrmann, Franziska Kolek, Vivien Leier‐Wirtz, Swetlana Urban, Bärbel Foesel, Michael Schloter, Madhumita Bhattacharyya, Ioana Pyrri, Matthias Reiger, Vera Schwierzeck, Claudia Hülpüsch, Claudia Traidl‐Hoffmann, Athanasios Damialis, Stefanie Gilles   +15 more
wiley   +1 more source

Beyond social media users and game players: patterns of digital media use and their association with personality traits. [PDF]

Front Psychol
Stojković I, Mentus T, Jelić M, Filipović B, Veselinović M.   +4 more
europepmc   +1 more source

Understanding Fathers Engagement: Contextual Insights From Tajikistan and Azerbaijan

Children &Society, EarlyView.
ABSTRACT Research on parental engagement often portrays fathers as less involved in their children's lives compared to mothers. This paper challenges such a perspective by examining fathers' engagement within the socio‐cultural contexts of Tajikistan and Azerbaijan.
Zarina Muminova, Sabina Savadova, Janet Goodall   +2 more
wiley   +1 more source

Case Report: Bloodstream infection due to <i>Clostridium innocuum</i> combined with <i>Eggerthella lenta</i>. [PDF]

Front Med (Lausanne)
Xu Y, Xu A, Du J, Zhao Y, Liu X, Sun Z, Xu Q, Zhang M, Tian YR.   +8 more
europepmc   +1 more source