Results 81 to 90 of about 141,920 (285)

Gut Bacteria Improve Depressive Symptoms by Degrading Cortisol into Androgen

open access: yesAdvanced Science, EarlyView.
Chronic stress is an important risk factor for stress‐related disorders such as depression. Stress hormone cortisol is essential for the pathogenesis of stress‐related disorders such as depression. Some gut microbiota degraded cortisol, and improve depressive symptoms.
Xiong Wang   +12 more
wiley   +1 more source

Vulnerabilities and responsibilities: dealing with monsters in computer security [PDF]

open access: yes, 2009
Purpose – The purpose of this paper is to analyze information security assessment in terms of cultural categories and virtue ethics, in order to explain the cultural origin of certain types of security vulnerabilities, as well as to enable a proactive ...
Consoli, L., Pieters, W.
core   +4 more sources

Anti‐PD‐1 Nanobody‐Armored MSLN CAR‐T Therapy for Malignant Mesothelioma: Preclinical and Clinical Studies

open access: yesAdvanced Science, EarlyView.
A novel therapy using engineered immune cells (NAC‐T cells) showed promise for refractory malignant mesothelioma. Based on the encouraging preclinical data, the first‐in‐human trial is initiated, demonstrating tolerable safety and promising anti‐tumor activity (ORR 63.6%, DCR 100%, including one CR).
Yan Sun   +23 more
wiley   +1 more source

Siete al mondo, non c’è rimedio! Nostalgie e xenalgie più o meno contemporanee = You’re on earth, there’s no cure for that! More or less contemporary nostalgia and xenalgia

open access: yesH-ermes: Journal of Communication, 2016
Nostalgia may be considered as a particular mood (Stimmung) or a peculiar form of being (Dasein). Sometimes it can also degenerate into psychopathological disorders as “lived time” and “lived space” chronic alterations.
Elena Gigante
doaj   +1 more source

‘Ten Years Ahead of His Time’: The East End Elegance of Martin Peters [PDF]

open access: yes, 2015
Martin Peters was a successful footballer whose public persona matched the way he played the game, without fuss or fanfare. A key English player of the 1960s, he does not usually feature in discussions about the connection between fashion and football in
Hughson, John Ewing
core   +1 more source

Hyperviscous Diabetic Bone Marrow Niche Impairs BMSCs Osteogenesis via TRPV2‐Mediated Cytoskeletal‐Nuclear Mechanotransduction

open access: yesAdvanced Science, EarlyView.
Diabetic bone marrow exhibits pathological ECM hyperviscosity that activates TRPV2‐mediated Ca2⁺ influx, leading to perinuclear F‐actin disassembly, nuclear deformation, and chromatin condensation. This cytoskeletal‐nuclear decoupling suppresses osteogenic differentiation of BMSCs.
Yao Wen   +8 more
wiley   +1 more source

Radicalism and the limits of reform : the case of John Reed [PDF]

open access: yes, 1980
Poet, journalist, editorial board member of the Masses and founding member of the Communist Labor Party, John Reed is a hero in both the worlds of cultural and political radicalism.
Rosenstone, Robert A.
core  

Endometrial Assembloid Model Reveals Endometrial Gland Development Regulation by Estradiol‐Driven WNT7B Suppression

open access: yesAdvanced Science, EarlyView.
This study developed a 3D endometrial assembloid model to study how uterine glands form and develop. They discovered key interactions between different cell types and identified WNT7B as a regulator controlled by estradiol‐mediated TGFβ1‐VDR interaction.
Xintong Li   +12 more
wiley   +1 more source

Utbredt men annerledes

open access: yesTidsskrift for Samfunnsforskning, 2011
Blant unge menn i slutten av tjueårene har en av tre prøvd cannabis. Det er også en utbredt forståelse at hasj er blitt et “normalt” rusmiddel, på linje med alkohol. I forskningslitteraturen er dette kjent som kulturell normalisering.
Sveinung Sandberg
doaj   +1 more source

A qualitative exploration of whether lesbian and bisexual women are 'protected' from sociocultural pressure to be thin [PDF]

open access: yes, 2014
Heterosexual women in Western cultures are known to experience body image concerns, dieting and disordered eating as a result of intense social pressures to be thin. However, it is theorised that lesbian and bisexual women belong to a subculture that is ‘
Brown LS   +6 more
core   +1 more source

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