Results 111 to 120 of about 101,554 (283)

Targeting the GPX4–FUNDC1 Interaction with Magnesium Lithospermate B Attenuates Sepsis‐Associated Lung Injury

open access: yesAdvanced Science, EarlyView.
The diagram depicts the endothelial‐protective mechanism of magnesium lithospermate B (MLB) in sepsis‐associated lung injury. MLB binds GPX4 at Gly79, disrupts its interaction with FUNDC1, prevents mitophagy‐mediated GPX4 degradation, restores mitophagic flux, reduces ROS, and limits ferroptosis.
Zhixi Li   +10 more
wiley   +1 more source

Étudier les musiques populaires : culture, économie, politique. Entretien avec Gérôme Guibert

open access: yesTransposition
In this interview, sociologist Gérôme Guibert reflects on Popular Music Studies’ history. Guibert, who has contributed to the development of this field of study in France, discusses recent research on metal music and subcultures, an area to which he has ...
Andrée Friaud, Maël Hamey Jakubowicz
doaj   +1 more source

Thermally Gated Dual‐Cascade Nanozyme for Enhanced Mild‐Temperature Photothermal Therapy

open access: yesAdvanced Science, EarlyView.
A thermo‐responsive cascade nanozyme (Ru‐GOx‐PNN) synergistically enhances mild photothermal therapy by dual suppression of HSP70 through ROS‐induced lipid peroxidation and ATP depletion. This intelligent system effectively overcomes thermotolerance and amplifies apoptosis, offering a safe and precise strategy for tumor treatment.
Shuyu Wang   +7 more
wiley   +1 more source

Etnografía subcultural

open access: yes, 1974
"Lara, Fernando, 1947-" tambi?n ha firmado sus art?culos como "Valle, Ram?n"
openaire   +1 more source

Mechanical Stimuli‐Induced Manipulation of Malignant Behavior in Bioprinted Cancer Microtissues via PI3K/NF‐κB Activation

open access: yesAdvanced Science, EarlyView.
A mechanically tunable ECM platform is created by integrating dECM–alginate matrices with in‐bath tumor printing. The mechanically tunable ECM environment drives tumors to acquire hypoxia, mechanotransduction signaling, metastatic traits, and drug‐resistant phenotypes that collectively promote malignant transformation.
Seok‐Hyeon Lee   +8 more
wiley   +1 more source

BRINGING OUT THE “CAL” IN GLOCAL: SITUATING SUBCULTURE AND DIGITAL SUBCULTURES IN TURKISH YOUTH

open access: yesGlocalism: Journal of Culture, Politics and Innovation
In a globalized postmodern world, the metanarratives of modernity are contested and have been paving the way for a patchwork of cultures and subcultures.
faydogan Filiz Aydogan Boschele
doaj   +1 more source

Microgel‐Based Hierarchical Porous Hydrogel Patch with Adhesion and Resilience for Myocardial Infarction

open access: yesAdvanced Science, EarlyView.
This study develops a hierarchically porous hydrogel patch strategy (HPMP), based on gas‐shearing microfluidics and an aqueous two‐phase system to fabricate porous microgels as microgel‐based bioinks. The porous microgels with controllable porous structure exhibit excellent cellular behavior.
Ziyang Liu   +13 more
wiley   +1 more source

Sites of Resistance: All-Ages Music Venues in their Local and Theoretical Contexts [PDF]

open access: yes, 2008
This paper shows how all-ages venues resist and contradict basic assumptions behind sociological, cultural policy and "creative cities" approaches to grassroots culture.
Tim Jones, Tim Wood
core  

Microglial GPR35 Ameliorates Epileptogenesis and Neuroinflammation via PDGFA Domain 2 Signaling

open access: yesAdvanced Science, EarlyView.
Activation of microglial G protein–coupled receptor 35 (GPR35) by L‐kynurenic acid (L‐Kyna) initiates a platelet‐derived growth factor A (PDGFA)–dependent phosphoinositide 3‐kinase–protein kinase B (PI3K–AKT) signaling cascade that dampens hippocampal neuroinflammation, thereby restraining epileptogenesis, lowering seizure susceptibility, and ...
Qi Wang   +17 more
wiley   +1 more source

Two theoretical dimensions of the cyber hate crime [PDF]

open access: yes, 2017
The impact and relationship between technologies and society establish the development of certain adaptive models, based on coexistence (Human-information-Machine), as well as several behavioral and cognitive changes of the human being, and new models of
Salas, Cesar Rommel
core  

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