Results 151 to 160 of about 101,554 (283)

Lithospermic Acid Improves Doxorubicin‐Induced Cardiomyopathy Through Sirtuin‐3‐Mediated Deacetylation of p53

open access: yesPhytotherapy Research, EarlyView.
Lithospermic acid (LA) inactivates the p53 signaling pathway via directly targeting SIRT3, thereby alleviating oxidative stress and abnormal apoptosis in the progression of doxorubicin (Dox)‐induced cardiomyocytes. ABSTRACT Doxorubicin (Dox)‐induced cardiomyopathy (DIC) is characterized by significant myocardial damage that can progress to dilated ...
Yining Zhao   +13 more
wiley   +1 more source

Protecting double Holliday junctions ensures crossing over during meiosis. [PDF]

open access: yesNature
Tang S   +11 more
europepmc   +1 more source

PEARL: Protein Eluting Alginate with Recombinant Lactobacilli

open access: yesSmall, EarlyView.
Probiotic lactobacilli meet engineered living materials: This study introduces PEARL (protein eluting alginate with recombinant lactobacilli), an innovative engineered living material combining Lactiplantibacillus plantarum and alginate beads for controlled protein release.
Varun Sai Tadimarri   +7 more
wiley   +1 more source

Evidence for Drop‐Like Nuclear Deformation in Sheared Endothelial Monolayers

open access: yesSmall, EarlyView.
Physiological shear stress smoothens endothelial monolayers by selectively eliminating less‐spread cells with tall, wrinkled nuclei. Nuclear volume and surface area remain constant, consistent with drop‐like deformation governed by geometric constraints.
Mohammad Mohajeri   +7 more
wiley   +1 more source

Multifunctional Porous Microshuttles as Scaffolding Components and Carriers of Bioactive Factors in Self‐Assembled Microtissues

open access: yesSmall, EarlyView.
This study introduces multifunctional, bioactive factor‐loaded porous microshuttles fabricated via a one‐step emulsification and chemical etching method. The poly(lactic‐co‐glycolic acid) microshuttles, featuring tunable pore sizes, enable loading and release of bioactive factors, and thereby enhance osteogenic marker expression and promote endothelial
Ke Song   +5 more
wiley   +1 more source

Facts and Hopes for Neoantigen-Enriched TIL. [PDF]

open access: yesClin Cancer Res
Brough SC   +4 more
europepmc   +1 more source

Cell Culture Substrate Variation Alters Extracellular Vesicle Biogenesis Without Affecting Non‐Coding Repeat RNA Profile

open access: yesSmall, EarlyView.
Cell culture biomechanical conditions influence extracellular vesicles (EVs) production in patient‐derived pancreatic adenocarcinoma (PDAC) cell lines. When grown in 3D conformation and in hydrogels with lower elasticity (0.5kPA), PDAC cells produce higher numbers of EVs, compared with cells grown in 2D on classic cell culture plastic.
Sara I. Veiga   +9 more
wiley   +1 more source

Home - About - Disclaimer - Privacy