Results 61 to 70 of about 22,146 (239)
Advanced Science, EarlyView.This study, through multi‐omics approaches and animal models, revealed that air pollutant PM10 exacerbates the progression of rheumatoid arthritis (RA) by suppressing FNBP1 expression and impairing the cytotoxic function of CD56dim NK cells. The “PM10–FNBP1–NK cells” axis provided novel insights into the environmental pathogenesis of RA and suggested ...
Runhan Zhao +11 more
wiley +1 more source
Advanced Science, EarlyView.This work introduces a scalable, data‐driven strategy that turns the vast sequence diversity of phage receptor‐binding proteins into modular tools for engineering customizable phages. By clustering and experimentally validating diverse RBPs, the authors build an accurate map linking sequence to host specificity and create plug‐and‐play modules that ...
Shisong Jing +10 more
wiley +1 more source
Frontiers in Psychology, 2018 We argue that two society-level properties—resistance to change and diversity within a culture—significantly affect agents' degrees of marginalization, which is here defined as access to cultural knowledge and institutional means for accomplishing ...
Charles Lassiter +3 more
doaj +1 more source
Advanced Science, EarlyView.The diagram depicts the endothelial‐protective mechanism of magnesium lithospermate B (MLB) in sepsis‐associated lung injury. MLB binds GPX4 at Gly79, disrupts its interaction with FUNDC1, prevents mitophagy‐mediated GPX4 degradation, restores mitophagic flux, reduces ROS, and limits ferroptosis.
Zhixi Li +10 more
wiley +1 more source
Youth subcultures in the world of popular culture
Освітологія, 2017 The autor discusse the issues of the symbolic and material world born out of subcultural currents. The activity of the most distinctive youth subcultures has also been presented over the last decades.
Gebel Tomasz
doaj +1 more source
Sphingomonas paucimobilis‐Driven Epithelial–Endothelial Transition in Adenomyosis Pathogenesis
Advanced Science, EarlyView.This study identifies epithelial–endothelial transition (EET) as a novel adenomyosis pathogenic mechanism driven by Sphingomonas paucimobilis colonization. Systematic inhibitor experiments validate a TNFα→NF‐κB→MMP signaling cascade essential for EET. Critically, bacterial culture supernatant fails to induce pathological changes, demonstrating viable ...
Peigen Chen +7 more
wiley +1 more source
Thermally Gated Dual‐Cascade Nanozyme for Enhanced Mild‐Temperature Photothermal Therapy
Advanced Science, EarlyView.A thermo‐responsive cascade nanozyme (Ru‐GOx‐PNN) synergistically enhances mild photothermal therapy by dual suppression of HSP70 through ROS‐induced lipid peroxidation and ATP depletion. This intelligent system effectively overcomes thermotolerance and amplifies apoptosis, offering a safe and precise strategy for tumor treatment.
Shuyu Wang +7 more
wiley +1 more source
THE INFLUENCE OF AFRICAN CULTURE ON THE FORMATION OF SUBCULTURAL IDENTITY OF MODERN RASTAFARIAN
Sovremennye Issledovaniâ Socialʹnyh Problem, 2013 The research deals with youth movements as the means of personal self-identification of young people, which is the most effective way to study subcultures.
Эльвира Ринатовна Гатиатуллина
doaj +1 more source
Distinct Immunomodulatory Strategies Guide Mesenchymal Stromal/Stem Cell‐Mediated Bone Regeneration
Advanced Science, EarlyView.Bone regeneration by mesenchymal stem cells is strongly influenced by immune signals. This study shows that priming stem cells with regulatory immune cells or an inflammation‐resolving lipid molecule enhances bone formation through distinct immune pathways.
Salwa Suliman +5 more
wiley +1 more source
Проблеми сучасної психології, 2018 The article analyzes the specificity of value’s system of adolescent from informal unions with prevailing different tendencies in interpersonal communication.
V. А. Lavrinenko
doaj +1 more source