Results 131 to 140 of about 796,231 (315)

Identification of Post-Ictal Generalised EEG Suppression with Two-Channel EEG

Sensors
This study investigates the feasibility of using a two-channel subcutaneous EEG device (SubQ) to detect and monitor PGES. The SubQ device, developed by UNEEG Medical A/S, offers a minimally invasive alternative to scalp EEG, enabling ultra-long-term ...
Joe Davies, Ali Zarei, Jonas Duun-Henriksen, Pedro Viana, Sándor Beniczky, Mark P. Richardson   +5 more
doaj   +1 more source

Comparative clinical utility of once-weekly subcutaneous abatacept in the management of rheumatoid arthritis

, 2014
Chadi Rakieh, Philip G ConaghanLeeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds, UKAbstract: Biologic therapies in rheumatoid arthritis are now part of standard ...
Conaghan PG, Rakieh C
core  

Making the Case for Organ‐on‐Chip Platforms in Long‐Acting Therapeutics Development

Advanced Healthcare Materials, EarlyView.
LATs release drug from a tissue‐resident depot over weeks to months, improving adherence, but their development is hampered by preclinical models that cannot reproduce the coupled tissue processes, sustained release, local microenvironment change, interstitial transport, immune and foreign‐body responses, and clearance that govern depot performance in ...
Charlie Gowans, Abdulwahhab Khedr, Panagiotis G. Georgiou, Nehir Arik, Ozlem Sen, Steve P. Rannard, Tom O. McDonald, Christos Tapeinos   +7 more
wiley   +1 more source

Subcutaneous rhinosporidiosis

Indian Journal of Dermatology, 2008
Nayak Surajit, Rout Tapas, Acharjya Basanti, Patra Manoj   +3 more
openaire   +3 more sources

2‐Deoxyglucose Dendrimer‐Enabled Niclosamide Delivery to FRβ‐Expressing Macrophages Alleviates Endometriosis Progression and Associated Hyperalgesia

Advanced Healthcare Materials, EarlyView.
A folic acid (FA)‐conjugated 2‐deoxyglucose dendrimer selectively targets FRβ+ macrophages in endometriotic lesions, enabling precise intracellular delivery of niclosamide. This nonhormonal nanomedicine enhances drug solubility, provides controlled intracellular release, suppresses lesion growth, reduces inflammation and pain, and establishes FRβ ...
Anubhav Dhull, Mingxin Shi, Madeleine E. Harvey, Taylor M. Page, Rishi Sharma, Kenneth John Goody, Aqib Iqbal Dar, Nash S. Moawad, Vijay Kumar Sirohi, Paul S. Cooke, Kanako Hayashi, Anjali Sharma   +11 more
wiley   +1 more source

Advancing Human Skin Equivalents: The Crucial Role of Neurovascular Integration

Advanced Healthcare Materials, EarlyView.
This review discusses the importance of integrating vascular and peripheral nerve systems into human skin equivalents (HSEs) to better recapitulate native skin physiology. Recent advances in vascularized, innervated, and neurovascularized HSEs are highlighted, together with emerging bioengineering strategies, current challenges, and future ...
Hao Wu, Lorenzo Moroni, Nicolas Lebonvallet, Vincent Flacher, Paul Wieringa   +4 more
wiley   +1 more source

Tolerability of immunoglobulin products and outcomes after product switching: a single-center real-world retrospective study

Frontiers in Immunology
ObjectivesWe assessed the frequency of adverse drureactions (ADRs) to immunoglobulin products, associated switching patterns, and tolerability after switching in clinical practice.MethodsThis observational, retrospective study was conducted at a single ...
Paulina Vásquez-Reyes, Andrea Ferranti-Ramos, Daniel Iguasnia Portilla, Helena Fernández-Cabrera, Isabel Castillo-Castillo, Oana Irina Sobieschi, Luis Fernandez Pereira   +6 more
doaj   +1 more source

Magnetically Driven Biofabrication for Tissue Engineering: From Nanoparticle Design to Mag‐ATMP Translation

Advanced Healthcare Materials, EarlyView.
Magnetically responsive nanoparticles enable remote control over biomaterials, cells, and engineered tissues. This review summarizes material design, biological safety, fabrication and actuation strategies, computational validation, and translational pathways that support the development of magnetic tissue‐engineering platforms and future magnetically ...
Konstantinos Ioannidis, Dimitrios Lefas, Maya Guilliams, Jackie Van Grootenbril, Isaak Decoene, Dimitrios Sakellariou, Bart Smeets, Stefanos Mourdikoudis, Ioannis Papantoniou   +8 more
wiley   +1 more source

Preincisional administration of intravenous or subcutaneous infiltration of low-dose ketamine suppresses postoperative pain after appendectomy

, 2011
Azim Honarmand, Mohammadreza Safavi, Hasan KarakyAnesthesiology and Critical Care Research Center, Isfahan University of Medical Sciences, Isfahan, IranBackground: Ketamine, an N-methyl-D-aspartate receptor antagonist, can suppress hyperalgesia and ...
A, Safavi M, Honarm, Karaky H
core  

Five-day regimen of intramuscular or subcutaneous self-administered adrenocorticotropic hormone gel for acute exacerbations of multiple sclerosis: a prospective, randomized, open-label pilot trial

, 2011
James P Simsarian, Carol Saunders, D Michelle SmithNeurology Center of Fairfax Ltd, Fairfax, VA, USABackground: Despite over 50 years of experience with adrenocorticotropic hormone (ACTH) as a treatment for acute exacerbations of multiple sclerosis ...
James Simsarian, Saunders C, Simsarian JP, Carol Saunders, Smith DM, Michelle Smith   +5 more
core   +1 more source